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[雄性家兔两个年龄组的血清脂质和脂蛋白组分]

[Serum lipid and lipoprotein fractions in 2 age groups of male rabbits].

作者信息

Kiriakov A, Tinterova Z, Stoianova S, Kavrŭkova Iu, Rashev M

出版信息

Eksp Med Morfol. 1980;19(3):165-72.

PMID:7418646
Abstract

The authors examined in 125 young sexually mature and in 50 young sexually immature male rabbits of a New Zealand improved Bulgarian breed the following serum lipid indices: total lipids, total and free cholesterol triglycerides, phospholipids, cholesterol and triglyceride content of VLDL (very low density lipoproteins), LDL (high density lipoproteins), HDL (high density lipoproteins) and the percentage concentration of serum lipopropteins, examined electrophoretically. The concentrations of the examined lipid and lipoprotein fractions in the sera of both age groups of rabbits showed asymetrical distribution. The hystograms of the total lipids and total cholesterol in younger animals was excluded. The logarithnictrandsformation of asymetricaly distributed concentrations of the examined fractions normalized their distribution in a part of them. The authors determined the ranges of the norm with the help of the percentile analysis in the remaining indices with asymetric distribution. Serum lipid and lipoprotein profile revealed substantial differnces in both age groups of animals. Serum lipids and lipoproteins in young sexually mature male rabbits differed from those of a man not only by their absolute concentrations, but also by their structural characteristics.

摘要

作者对125只性成熟的新西兰改良保加利亚品种幼龄雄兔和50只性未成熟的该品种幼龄雄兔的下列血清脂质指标进行了检测:总脂质、总胆固醇和游离胆固醇、甘油三酯、磷脂、极低密度脂蛋白(VLDL)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)中的胆固醇和甘油三酯含量,以及通过电泳检测的血清脂蛋白的百分比浓度。两个年龄组兔血清中所检测的脂质和脂蛋白组分的浓度呈不对称分布。排除了幼龄动物中总脂质和总胆固醇的直方图。对所检测组分的不对称分布浓度进行对数转换,使其中一部分的分布得以归一化。作者借助百分位数分析确定了其余不对称分布指标的正常范围。血清脂质和脂蛋白谱显示两个年龄组动物之间存在显著差异。性成熟幼龄雄兔的血清脂质和脂蛋白不仅在绝对浓度上与人类不同,而且在结构特征上也有所不同。

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