Maianskiĭ A N, RVssanov S P, Astafĕv D G, Osipov O A
Zh Mikrobiol Epidemiol Immunobiol. 1990 Mar(3):65-8.
The capacity of S. aureus peptidoglycan (PG) for inducing the luminol-dependent chemiluminescence of human lymphocytes has been studied. Lymphocytes taken from adult donors have been found to give dose-dependent reaction to S. aureus PG, while lymphocytes from newborn infants have been inert under the same conditions. Essential differences in the kinetics of response to PG (the maximum intensity of chemiluminescence occurs in 25-30 minutes) and to phytohemagglutinin (the maximum intensity is reached in 1 minute) were observed. These results are considered as the manifestation of specific sensitization to bacterial peptidoglycans, which may be rapidly detected by reactive chemiluminescence.
已经研究了金黄色葡萄球菌肽聚糖（PG）诱导人淋巴细胞鲁米诺依赖性化学发光的能力。发现取自成年供体的淋巴细胞对金黄色葡萄球菌PG产生剂量依赖性反应，而在相同条件下新生儿的淋巴细胞则无反应。观察到对PG（化学发光的最大强度在25 - 30分钟出现）和对植物血凝素（最大强度在1分钟达到）的反应动力学存在本质差异。这些结果被认为是对细菌肽聚糖特异性致敏的表现，可通过反应性化学发光快速检测到。
