Maianskiĭ A N, Sibiriakova N I, Astaf'ev D G, Fokina Iu V
Zh Mikrobiol Epidemiol Immunobiol. 1993 Mar-Apr(2):114-8.
The peptidoglycan activity of Staphylococcus aureus CCM 885 and Bifidobacterium bifidum 1 was studied in the opsonophagocytic system on the basis of the luminol-dependent chemiluminescence of human neutrophils. B. bifidum peptidoglycan was more active in direct interaction with neutrophils. After treatment with normal human serum S. aureus peptidoglycan showed more pronounced neutrophil-stimulating properties. This phenomenon was in accord with a higher content of IgG antibodies to S. aureus peptidoglycan, as well as with its capacity for the classical direct activation of the complement. Moreover, in reactions with S. aureus peptidoglycan "minor" opsonins, independent of antibodies and complement, were detected. B. bifidum peptidoglycan did not activate the complement, could not be opsonized with the serum having no specific antibodies and did not react with "minor" opsonins.
基于人中性粒细胞的鲁米诺依赖性化学发光，在调理吞噬系统中研究了金黄色葡萄球菌CCM 885和两歧双歧杆菌1的肽聚糖活性。两歧双歧杆菌肽聚糖在与中性粒细胞的直接相互作用中更具活性。用正常人血清处理后，金黄色葡萄球菌肽聚糖表现出更明显的刺激中性粒细胞的特性。这一现象与针对金黄色葡萄球菌肽聚糖的IgG抗体含量较高以及其经典直接激活补体的能力一致。此外，在与金黄色葡萄球菌肽聚糖的反应中，检测到了独立于抗体和补体的“次要”调理素。两歧双歧杆菌肽聚糖不激活补体，不能被没有特异性抗体的血清调理，也不与“次要”调理素反应。
