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[人类白内障中晶状体上皮细胞的密度和六边形化]

[Cell density and hexagonality of lens epithelium in human cataracts].

作者信息

Saitoh J, Nishi O, Hitani H

机构信息

Nishi Eye Hospital, Osaka, Japan.

出版信息

Nippon Ganka Gakkai Zasshi. 1990 Feb;94(2):176-80.

PMID:2368644
Abstract

One hundred and ninety flat preparations of human lens epithelium attached to the anterior capsule, obtained during surgical extracapsular cataract extraction (ECCE), were studied. The median cell density of all preparations was 4,701 cells/sqmm. The lens epithelium of the patients exceeding 50 years of age showed lower density than that of younger patients (p less than 0.05). The epithelium of females showed a higher density than that of male patients. With increasing maturity of cataracts, the cell density decreased (p less than 0.05). Moreover the cell density of DM patients was significantly lower than that of non-DM patients (p less than 0.05). This result may be explained by the sorbitol pathway theory. There were no significant differences among any cases in term of hexagonality.

摘要

对在白内障囊外摘除术(ECCE)过程中获取的190份附着于前囊的人晶状体上皮平铺标本进行了研究。所有标本的细胞密度中位数为4701个细胞/平方毫米。50岁以上患者的晶状体上皮密度低于年轻患者(p<0.05)。女性患者的上皮细胞密度高于男性患者。随着白内障成熟度增加,细胞密度降低(p<0.05)。此外,糖尿病患者的细胞密度显著低于非糖尿病患者(p<0.05)。这一结果可用山梨醇途径理论来解释。在六边形方面,各病例之间无显著差异。

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1
[Cell density and hexagonality of lens epithelium in human cataracts].[人类白内障中晶状体上皮细胞的密度和六边形化]
Nippon Ganka Gakkai Zasshi. 1990 Feb;94(2):176-80.
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[Changes in the lens epithelium of diabetic and non-diabetic patients with various forms of opacities in senile cataract].[老年白内障不同类型混浊的糖尿病和非糖尿病患者晶状体上皮的变化]
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Mol Vis. 2014 May 21;20:661-9. eCollection 2014.
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A prospective evaluation of posterior capsule opacification in eyes with diabetes mellitus: a case-control study.糖尿病患者眼部后囊膜混浊的前瞻性评估:一项病例对照研究。
Eye (Lond). 2014 Jun;28(6):720-7. doi: 10.1038/eye.2014.60. Epub 2014 Mar 28.
3
Changes in the lens epithelium with respect to cataractogenesis: light microscopic and Scheimpflug densitometric analysis of the cataractous and the clear lens of diabetics and non-diabetics.
晶状体上皮细胞在白内障形成过程中的变化:糖尿病患者和非糖尿病患者白内障晶状体与透明晶状体的光学显微镜及Scheimpflug密度测定分析
Graefes Arch Clin Exp Ophthalmol. 2006 May;244(5):596-602. doi: 10.1007/s00417-005-0091-7. Epub 2005 Sep 21.
4
Lens epithelial changes and mutated gene expression in patients with myotonic dystrophy.强直性肌营养不良患者的晶状体上皮变化及突变基因表达
Br J Ophthalmol. 1999 Apr;83(4):452-7. doi: 10.1136/bjo.83.4.452.