Dipartimento di Matematica, Modellistica e Calcolo Scientifico (MOX), Politecnico di Milano, Via Bonardi 9, 20133 Milano, Italy.
Comput Math Methods Med. 2013;2013:373401. doi: 10.1155/2013/373401. Epub 2013 Apr 18.
Atrial Fibrillation (AF) is the most common cardiac arrhythmia. It naturally tends to become a chronic condition, and chronic Atrial Fibrillation leads to an increase in the risk of death. The study of the electrocardiographic signal, and in particular of the tachogram series, is a usual and effective way to investigate the presence of Atrial Fibrillation and to detect when a single event starts and ends. This work presents a new statistical method to deal with the identification of Atrial Fibrillation events, based on the order identification of the ARIMA models used for describing the RR time series that characterize the different phases of AF (pre-, during, and post-AF). A simulation study is carried out in order to assess the performance of the proposed method. Moreover, an application to real data concerning patients affected by Atrial Fibrillation is presented and discussed. Since the proposed method looks at structural changes of ARIMA models fitted on the RR time series for the AF event with respect to the pre- and post-AF phases, it is able to identify starting and ending points of an AF event even when AF follows or comes before irregular heartbeat time slots.
心房颤动(AF)是最常见的心律失常。它通常会发展为慢性疾病,而慢性心房颤动会增加死亡风险。对心电图信号的研究,特别是心动过速系列的研究,是一种常用且有效的方法,可以调查心房颤动的存在,并检测单个事件的开始和结束时间。这项工作提出了一种新的统计方法,用于基于描述表征 AF 不同阶段(AF 前、AF 期间和 AF 后)的 RR 时间序列的 ARIMA 模型的阶数识别,来处理心房颤动事件的识别。进行了一项模拟研究,以评估所提出方法的性能。此外,还提出并讨论了针对患有心房颤动的患者的实际数据的应用。由于所提出的方法着眼于针对 AF 事件的 RR 时间序列上拟合的 ARIMA 模型的结构变化,因此即使 AF 紧随不规则心跳时隙之后或之前,它也能够识别 AF 事件的开始和结束点。