Akselrod S, Gordon D, Ubel F A, Shannon D C, Berger A C, Cohen R J
Science. 1981 Jul 10;213(4504):220-2. doi: 10.1126/science.6166045.
Power spectrum analysis of heart rate fluctuations provides a quantitative noninvasive means of assessing the functioning of the short-term cardiovascular control systems. We show that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz. Our data therefore provide evidence that the renin-angiotensin system plays a significant role in short-term cardiovascular control in the time scale of seconds to minutes.
心率波动的功率谱分析提供了一种评估短期心血管控制系统功能的定量无创方法。我们表明，交感神经和副交感神经活动对心率功率谱有频率特异性贡献，并且肾素-血管紧张素系统活动强烈调节位于0.04赫兹处的频谱峰值幅度。因此，我们的数据提供了证据，表明肾素-血管紧张素系统在秒到分钟的时间尺度上的短期心血管控制中起重要作用。
