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HIV感染患者的结核相关免疫重建炎症综合征(TB-IRIS):两例报告及文献综述

Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview.

作者信息

Viskovic Klaudija, Begovac Josip

机构信息

Department of Radiology and Ultrasound, University Hospital for Infectious Diseases, Mirogojska Cesta 8, 10000 Zagreb, Croatia.

出版信息

Case Rep Infect Dis. 2013;2013:323208. doi: 10.1155/2013/323208. Epub 2013 Apr 18.

Abstract

We describe two HIV-infected patients with tuberculosis-associated immune reconstruction inflammatory syndrome (TB-IRIS): one with "paradoxical" IRIS and the other with "unmasking" IRIS. TB-IRIS in HIV-infected subjects is an exacerbation of the symptoms, signs, or radiological manifestations of a pathogenic antigen, related to recovery of the immune system after immunosuppression. We focused on the radiological characteristics of TB-IRIS and the briefly literature review on this syndrome.

摘要

我们描述了两名患有结核病相关免疫重建炎症综合征(TB-IRIS)的HIV感染患者:一名患有“矛盾性”IRIS,另一名患有“揭露性”IRIS。HIV感染受试者中的TB-IRIS是致病抗原的症状、体征或放射学表现的加重,与免疫抑制后免疫系统的恢复有关。我们重点关注了TB-IRIS的放射学特征,并对该综合征进行了简要的文献综述。

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