Headache Unit, Department of Clinical Neuroscience, C. Besta Neurological Institute and Foundation, Via Celoria, 11, 20133 Milan, Italy.
Neurol Sci. 2013 May;34 Suppl 1:S29-31. doi: 10.1007/s10072-013-1362-4.
The aim of this paper is to review hypotheses regarding pain mechanisms in headache and relationships between headache pain and the brain's emotional network. There is evidence that chronic pain in idiopathic headaches is, in part, an emotional response induced by alterations in the homeostasis of the interoceptive system--a system that integrates nociceptive information with the emotional network (mediating emotional awareness). These findings suggest that idiopathic headaches are probably due to both an altered pain matrix on the one hand, and an altered affective-cognitive state on the other.
本文旨在回顾关于头痛疼痛机制的假说以及头痛疼痛与大脑情绪网络之间的关系。有证据表明，特发性头痛的慢性疼痛部分是由内感受系统稳态改变引起的情绪反应，内感受系统整合伤害性信息和情绪网络（介导情绪感知）。这些发现表明，特发性头痛可能一方面是由于疼痛矩阵改变，另一方面是由于情感认知状态改变所致。
