VA Boston Healthcare System, National Center for PTSD, Women's Health Sciences Division, Boston, MA 02130, USA.
J Trauma Stress. 2013 Jun;26(3):319-28. doi: 10.1002/jts.21818. Epub 2013 May 20.
The mediating role of posttraumatic stress symptomatology (PSS) on the association between warzone exposure and physical health symptoms in 7 bodily systems (cardiovascular, dermatological, gastrointestinal, genitourinary, musculoskeletal, neurological, and pulmonary) was examined. We also examined if mediation effects varied as a function of sex. A sample of 317 U.S. Gulf war veterans was assessed for warzone exposure, PSS, and physical health symptoms 10 years after deployment. PSS was significantly associated with postdeployment physical health in all symptom categories when accounting for predeployment health (with effect sizes ranging from a 1.27-1.64 increase in the likelihood of postdeployment physical health symptoms with a 1 standard deviation increase in the PSS symptoms). PSS severity mediated the relationship between warzone exposure and postdeployment symptoms in all physical health domains (with percent mediation ranging 44%-75%). A significant Warzone Exposure × PSS interaction emerged for 5 outcomes such that the effect of PSS on physical health was stronger for veterans reporting lower warzone exposure. No significant interactions with sex emerged. These findings suggest the important influence of PSS on physical health symptoms for both men and women.
创伤后应激症状（PSS）在战区暴露与 7 个身体系统（心血管、皮肤、胃肠道、泌尿生殖、肌肉骨骼、神经和肺）的身体健康症状之间的关联中的中介作用进行了研究。我们还研究了性别是否会影响中介效应。在部署后 10 年，对 317 名美国海湾战争退伍军人进行了战区暴露、PSS 和身体健康症状评估。在考虑到部署前健康状况的情况下，PSS 与所有症状类别中的部署后身体健康状况显著相关（当 PSS 症状增加 1 个标准差时，发生部署后身体健康症状的可能性增加 1.27-1.64）。PSS 严重程度在所有身体健康领域（44%-75%的中介百分比）中介导了战区暴露与部署后症状之间的关系。对于 5 个结果，出现了显著的战区暴露 × PSS 相互作用，即对于报告战区暴露较低的退伍军人，PSS 对身体健康的影响更强。没有出现与性别相关的显著相互作用。这些发现表明 PSS 对男女身体健康症状的重要影响。
