Malenkov A G, Modianova E A, Kolotygina I M
Biofizika. 1990 Mar-Apr;35(2):356-60.
Studies of changes in the cells adhesive force during spontaneous and induced cancerogenesis, as well as under the effect of cancerogenesis promotors permits to reveal the cells adhesion forces critical values which separate tissue states stable and unstable to blastomogenesis. These data are analysed proceeding from the concepts on generalized cooperative transitions in the membranes and their role in the control over biological systems. It is taken into account that the membranes and cytoskeleton elements are the most important systems of the tissue mechanical integration, and phase transitions proceeding in them must be reflected in the tissue mechanical properties.
对自发和诱导致癌过程中细胞黏附力的变化，以及在致癌促进剂作用下细胞黏附力变化的研究，有助于揭示细胞黏附力的临界值，这些临界值区分了对成瘤稳定和不稳定的组织状态。这些数据是根据关于膜中广义协同转变及其在生物系统控制中的作用的概念进行分析的。考虑到膜和细胞骨架成分是组织机械整合的最重要系统，其中发生的相变必定会在组织力学性质中得到反映。
