Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.
Muscle Nerve. 2013 Jul;48(1):137-9. doi: 10.1002/mus.23767. Epub 2013 May 22.
Cervical spondylosis (CS) is a common disease in adults and may coexist with amyotrophic lateral sclerosis (ALS). It is important to detect ALS coexisting with CS (ALS-cs) at an early stage, especially when surgical treatment of CS is planned.
Single-fiber electromyography was performed in 26 patients with ALS, 19 with ALS-cs, and 22 with CS.
Mean jitter, percentage of jitter >55 μs, and percentage of impulse blocking were not statistically different between ALS and ALS-cs cases, but they were significantly lower in CS. Mean fiber density was not statistically different among the 3 groups. The percentage of pairs with jitter >55 μs exceeding 40% and mean jitter exceeding 55 μs had high sensitivity and specificity in the diagnosis of ALS.
Single-fiber electromyography can supply valuable information in helping to differentiate ALS from CS.
颈椎病（CS）是一种常见的成人疾病，可能与肌萎缩侧索硬化症（ALS）并存。早期发现伴有 CS 的 ALS（ALS-cs）非常重要，尤其是在计划对 CS 进行手术治疗时。
对 26 例 ALS 患者、19 例 ALS-cs 患者和 22 例 CS 患者进行单纤维肌电图检查。
ALS 和 ALS-cs 病例之间的抖动均值、大于 55 μs 的抖动百分比和冲动阻断百分比没有统计学差异，但在 CS 中明显较低。三组的纤维密度均值没有统计学差异。对于抖动大于 55 μs 的对的百分比大于 40%和抖动均值大于 55 μs 的情况，在 ALS 的诊断中具有较高的灵敏度和特异性。
单纤维肌电图可以提供有价值的信息，有助于将 ALS 与 CS 区分开来。
