Terada Tadashi
Department of Pathology, Shizuoka City Shimizu Hospital, Shimizu, Shizuoka, Japan.
Int J Clin Exp Pathol. 2013 May 15;6(6):1187-9. Print 2013.
Hybrid tumor composed of epidermal cyst and pilomatricoma has been reported in only four times in the English literature. Herein, a cutaneous hybrid tumor composed of epidermal cyst and cystic pilomatricoma in a 58-year-old woman was presented. The tumor was located in the scalp, and measured 1 x 1 x 1 cm. The tumor was cystic and contained atheromatous materials. Histologically, the cyst was composed of epidermal cyst (50% in area) and pilomatricoma (50% in area). The pilomatricoma was composed mostly of basophilic cells. Interestingly, the pilomatricoma element of the cyst showed immunoreactive p53 and Ki-67 (labeling=40%). In conclusion, the fifth case of hybrid tumor composed of epidermal cyst and pilomatricoma was presented.
英文文献中仅报道过4例由表皮囊肿和毛发上皮瘤组成的混合性肿瘤。本文报告了1例58岁女性患者，其皮肤混合性肿瘤由表皮囊肿和囊性毛发上皮瘤组成。肿瘤位于头皮，大小为1×1×1厘米。肿瘤呈囊性，内含粥样物质。组织学检查显示，囊肿由表皮囊肿（面积占50%）和毛发上皮瘤（面积占50%）组成。毛发上皮瘤主要由嗜碱性细胞构成。有趣的是，囊肿中的毛发上皮瘤成分显示p53和Ki-67免疫反应阳性（标记率=40%）。总之，本文报告了第5例由表皮囊肿和毛发上皮瘤组成的混合性肿瘤。
