Sanusi Tutyana, Qu Xiaoying, Li Yanqiu, Zhang Jing, Wang Ming, Zhao Yun, Yang Zhen, An Xiangjie, Qian Yue, Wang Chunsen, Chen Hongxiang, Chen Siyuan, Huang Changzheng
Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430022, China.
Int J Clin Exp Pathol. 2013 Nov 15;6(12):3019-22. eCollection 2013.
The follicular hybrid is composed of more than two components of pilosebaceous unit. There are several studies of hybrid cyst, combination of trichilemmal and epidermoid cyst was the most frequently reported. In this paper, we reported one case of hybrid cyst composed of bullous pilomatricoma and epidermoid cyst. A 14-year-old girl was complaint of a solitary flesh-colored to erythematous nodule with flaccid appearance sized 3.2 × 1.8 cm in diameter on her right upper back for one year. The histologic findings showed there were edema and proliferation of capillaries in the superficial dermis, a cyst in the middle to deep dermis. There were laminated keratins in the cystic space. The cyst wall was composed of two different components, one was composed of epithelial cells containing of granular layer, and another consisted of basophilic cells, transient cells and shadow cells. The cyst not related with Gardner's syndrome. Hybrid cyst such as trichilemmal cyst, epidermoid and pilomatricoma cysts maybe have same clinical features or mimicking each others, but we can distinguish them from histopathology evaluation.
滤泡性混合瘤由毛囊皮脂腺单位的两种以上成分组成。有多项关于混合性囊肿的研究，其中最常报道的是毛发囊肿与表皮样囊肿的组合。在本文中，我们报告了一例由大疱性毛母质瘤和表皮样囊肿组成的混合性囊肿。一名14岁女孩主诉右上背部有一个孤立的、肉色至红斑样、外观松弛、直径为3.2×1.8 cm的结节，病程一年。组织学检查发现，真皮浅层有水肿和毛细血管增生，真皮中深层有一个囊肿。囊腔内有板层状角蛋白。囊肿壁由两种不同成分组成，一种由含有颗粒层的上皮细胞组成，另一种由嗜碱性细胞、过渡细胞和影细胞组成。该囊肿与加德纳综合征无关。毛发囊肿、表皮样囊肿和毛母质瘤囊肿等混合性囊肿可能具有相同的临床特征或相互模仿，但我们可以通过组织病理学评估将它们区分开来。
