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甲型H1N1流感肺炎作为心脏移植后的早期并发症——来自克罗地亚萨格勒布杜布拉瓦大学医院的经验

The H1N1 influenza pneumonia as early complication after heart transplantation--experience from the Dubrava University Hospital, Zagreb, Croatia.

作者信息

Sicaja Mario, Sikić Jozica, Starcević Boris, Miklec Maria Nicole, Vince Adriana

机构信息

University of Zagreb, Dubrava University Hospital, Department of Cardiovascular Diseases, Zagreb, Croatia.

出版信息

Coll Antropol. 2013 Mar;37(1):309-11.

PMID:23697291
Abstract

In April 2009, a novel influenza A (H1N1) virus was initially detected, and only after two months World Health Organization declared pandemic, while virus became globally present. We report here a confirmed case of patient suffering from H1N1 influenza pneumonia in an early period after heart transplantation. Complications of influenza A and B include viral pneumonia, secondary bacterial pneumonia and possibly acute allograft rejection in the setting of weaning of immunosuppression. In our case H1N1 influenza pneumonia was treated according to the published guidelines and had a mild course of disease, but nevertheless emphasis should be put on the prevention of disease applying known general infection control procedures and vaccination while disease course cannot be predicted.

摘要

2009年4月,首次检测到一种新型甲型H1N1流感病毒,仅两个月后世界卫生组织就宣布该病毒在全球范围内流行。我们在此报告一例心脏移植术后早期确诊的甲型H1N1流感肺炎患者。甲型和乙型流感的并发症包括病毒性肺炎、继发性细菌性肺炎,在免疫抑制逐渐减少的情况下还可能出现急性移植排斥反应。在我们的病例中,甲型H1N1流感肺炎按照已发布的指南进行治疗,病程较轻,但仍应强调通过应用已知的常规感染控制措施和接种疫苗来预防疾病,因为疾病进程无法预测。

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