Rahimi S
Consultant Histopathologist, Pathology Centre, Queen Alexandra Hospital, Southwick Hill Road, Cosham, Portsmouth PO6 3LY, UK.
Clin Ter. 2013;164(2):143-7. doi: 10.7417/CT.2013.1534.
Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer in Caucasians, most frequently occurring on sun-exposed areas of the body. Most SCCs are treated surgically, either by excision or Mohs micrographic surgery. Despite the large amount of English literature with regard to cutaneous SCC in many instances the surgical treatment is not appropriate resulting in recurrences and/ or metastasis. The following brief review highlights the histology, molecular biology and surgical treatment of skin SCC.
皮肤鳞状细胞癌(SCC)是白种人中第二常见的皮肤癌,最常发生于身体暴露于阳光的部位。大多数皮肤鳞状细胞癌通过手术治疗,要么切除,要么采用莫氏显微外科手术。尽管有大量关于皮肤鳞状细胞癌的英文文献,但在很多情况下,手术治疗并不合适,会导致复发和/或转移。以下简要综述重点介绍皮肤鳞状细胞癌的组织学、分子生物学及手术治疗。