Zaiac M N, Weiss E
Department of Dermatology, Mount Sinai Medical Center, Greater Miami Skin and Laser Center, 4302 Alton Rd., Suite 1005, Miami Beach, FL 33140, USA.
Dermatol Surg. 2001 Mar;27(3):246-51.
The nail unit can be a challenging anatomic location for surgical removal of neoplasms. Although uncommon, malignancies do affect this specialized epithelial structure. In particular, Bowen's disease and more invasive squamous cell carcinoma (SCC) are the most common neoplasms to affect the nail unit and surrounding structures. Other neoplasms such as basal cell carcinoma and malignant melanoma can also affect the nail unit, but less frequently, and will not be discussed in the scope of this review. Mohs micrographic surgery continues to be the treatment of choice because of the procedure's tissue-sparing qualities. A clear understanding of the anatomy and the histology of the nail unit, a review of the technique of Mohs surgery of the nail anatomy, as well as a review of the literature are presented.
对于肿瘤的手术切除而言,甲单位是一个具有挑战性的解剖部位。尽管并不常见,但恶性肿瘤确实会影响这种特殊的上皮结构。特别是,鲍恩病和侵袭性更强的鳞状细胞癌(SCC)是最常影响甲单位及周围结构的肿瘤。其他肿瘤,如基底细胞癌和恶性黑色素瘤,也可影响甲单位,但较为少见,且不在本综述范围内讨论。由于莫氏显微外科手术具有保留组织的特性,它仍然是首选的治疗方法。本文将对甲单位的解剖学和组织学有清晰的认识,回顾甲部解剖结构的莫氏手术技术,并对相关文献进行综述。