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骨旁脂肪瘤。15例新病例报告及文献复习。

Parosteal lipoma. Report of 15 new cases and a review of the literature.

作者信息

Greco Manfredi, Mazzocchi Marco, Ribuffo Diego, Dessy Luca Andrea, Scuderi Nicolò

出版信息

Ann Ital Chir. 2013 Mar-Apr;84(2):229-35.

PMID:23698599
Abstract

The lipoma is the most common tumor of the body and can be found in virtually every tissue or organ. However, a parosteal lipoma is a rare benign fatty neoplasm having an intimate relationship to the periosteum. The incidence of this tumor is 0.3% of all lipomas. Over 150 cases of parosteal lipoma have previously been described in the literature. Owing to the rarity of this condition and the difficulties encountered in its diagnosis and treatment, we wish to report fifteen new cases of parosteal lipoma. We reviewed the clinical records of 15 patients who underwent surgery to remove a parosteal lipoma between November 2003 and July 2009. The diagnosis of a parosteal lipoma was made by the histological findings, the confirmation of fat content at Magnetic Resonance or Computed Tomography. Surgery in all the cases entailed resecting the tumor with parosteal excrescence. In three cases with hyperostosis, a further exeresis of the bone was performed. Parosteal lipomas are rare entities associated with periosteal involvement depending on their location. Current management should include computed tomographic scanning and magnetic resonance. Surgery, which is mandatory treatment, requires particular attention to ensure that any periosteal involvement is removed completely.

摘要

脂肪瘤是身体最常见的肿瘤,几乎可在每个组织或器官中发现。然而,骨旁脂肪瘤是一种罕见的良性脂肪肿瘤,与骨膜关系密切。该肿瘤的发病率占所有脂肪瘤的0.3%。此前文献中已描述过150多例骨旁脂肪瘤病例。鉴于这种疾病的罕见性以及其诊断和治疗中遇到的困难,我们希望报告15例新的骨旁脂肪瘤病例。我们回顾了2003年11月至2009年7月间接受手术切除骨旁脂肪瘤的15例患者的临床记录。骨旁脂肪瘤的诊断依据组织学检查结果,以及磁共振成像或计算机断层扫描对脂肪成分的确认。所有病例的手术均包括切除带有骨旁赘生物的肿瘤。在3例伴有骨质增生的病例中,进一步进行了骨切除。骨旁脂肪瘤是罕见的与骨膜受累相关的实体,具体取决于其位置。目前的治疗应包括计算机断层扫描和磁共振成像。手术是必要的治疗方法,需要特别注意确保完全切除任何骨膜受累部分。

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