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肿瘤性梅毒疹

Tumorous syphilid.

作者信息

Lee E S, Lee M G, Lee J B

机构信息

Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Genitourin Med. 1990 Jun;66(3):202-4. doi: 10.1136/sti.66.3.202.

DOI:10.1136/sti.66.3.202
PMID:2370064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1194503/
Abstract

An unusual form of secondary syphilis, characterised by oozing tumours on the forehead and scalp concomitantly with plaques in the genital area, is presented. The patient was diagnosed as having secondary syphilis by dark-field examination, serologic tests for syphilis, and demonstration of spirochetes in the tissues by the immunoperoxidase technique with avidin-biotin peroxidase complex. Treatment with benzathine penicillin led to rapid resolution of the skin lesions one month later. This case of tumorous syphilid, a variant of papular syphilid, which appears not to have been described in the literature previously.

摘要

本文报告了一种不寻常的二期梅毒,其特征为前额和头皮出现渗出性肿瘤,同时生殖器部位出现斑块。通过暗视野检查、梅毒血清学检测以及采用抗生物素蛋白-生物素过氧化物酶复合物的免疫过氧化物酶技术在组织中检测到螺旋体,该患者被诊断为二期梅毒。苄星青霉素治疗一个月后,皮肤病变迅速消退。此例肿瘤性梅毒疹是丘疹性梅毒疹的一种变体,此前文献中似乎未曾有过描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/a103cea41582/genitmed00045-0077-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/27d30a592b1c/genitmed00045-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/dd1aadaf567c/genitmed00045-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/29c17bd28223/genitmed00045-0077-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/a103cea41582/genitmed00045-0077-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/27d30a592b1c/genitmed00045-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/dd1aadaf567c/genitmed00045-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/29c17bd28223/genitmed00045-0077-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/1194503/a103cea41582/genitmed00045-0077-c.jpg

相似文献

1
Tumorous syphilid.肿瘤性梅毒疹
Genitourin Med. 1990 Jun;66(3):202-4. doi: 10.1136/sti.66.3.202.
2
Horny syphilid.结节性梅毒疹
Cutis. 1978 Jul;22(1):55-9.
3
A nodular syphilid presenting as a pseudolymphoma: mimicking a cutaneous marginal zone B-cell lymphoma.表现为假性淋巴瘤的结节性梅毒疹:酷似皮肤边缘区B细胞淋巴瘤。
Am J Dermatopathol. 2009 Dec;31(8):846-8. doi: 10.1097/DAD.0b013e3181ad4f22.
4
[Papular-nodular syphilid in a male patient with malignant syphilis].
Vestn Dermatol Venerol. 1975 Apr(4):89-92.
5
Follicular papulopustular syphilid.滤泡性丘疹脓疱性梅毒疹
Arch Dermatol. 1969 Oct;100(4):471-3.
6
Extensive annular verrucous late secondary syphilis.广泛环状疣状晚期二期梅毒。
Br J Dermatol. 2005 Jun;152(6):1343-5. doi: 10.1111/j.1365-2133.2005.06546.x.
7
Solitary framboesiform syphilid on the scalp.头皮上的孤立性杨梅样梅毒疹。
J Dermatol. 2012 Jun;39(6):568-9. doi: 10.1111/j.1346-8138.2011.01440.x. Epub 2011 Dec 5.
8
Papulonodular secondary syphilis: a rare clinic presentation confirmed by serologic and histologic exams.丘疹结节性二期梅毒:一种经血清学和组织学检查确诊的罕见临床表型。
An Bras Dermatol. 2016 Apr;91(2):205-7. doi: 10.1590/abd1806-4841.20163958.
9
[Disseminated pustulous-papulous syphilid in a female patient with secondary recurrent syphilis].[一名二期复发性梅毒女性患者的播散性脓疱丘疹性梅毒疹]
Vestn Dermatol Venerol. 1980 Jun(6):68-9.
10
Miliary pustular syphilid.
Cutis. 1984 Dec;34(6):556-8.

本文引用的文献

1
Condylomata lata of the palms: an unusual site.手掌部扁平湿疣:一个不寻常的部位。
Br J Vener Dis. 1980 Aug;56(4):267-8. doi: 10.1136/sti.56.4.267.
2
The great imitator, syphilis.“伟大的模仿者”——梅毒。
West J Med. 1981 May;134(5):424-32.
3
Secondary syphilis with framboesiform facial lesions: a case report.伴有杨梅样面部损害的二期梅毒:一例报告
Br J Vener Dis. 1981 Apr;57(2):103-5. doi: 10.1136/sti.57.2.103.
4
Secondary syphillis. Still the great imitator.
JAMA. 1983 Jun 10;249(22):3069-70. doi: 10.1001/jama.249.22.3069.
5
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.抗生物素蛋白-生物素-过氧化物酶复合物(ABC)在免疫过氧化物酶技术中的应用:ABC法与未标记抗体(PAP)法的比较。
J Histochem Cytochem. 1981 Apr;29(4):577-80. doi: 10.1177/29.4.6166661.
6
A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies.用放射免疫测定抗体研究多肽激素的过氧化物酶-抗过氧化物酶法与抗生物素蛋白-生物素复合物法的比较研究
Am J Clin Pathol. 1981 May;75(5):734-8. doi: 10.1093/ajcp/75.5.734.
7
An unusual solitary lesion of secondary syphilis.
Arch Dermatol. 1967 Feb;95(2):217.
8
Nodular secondary syphilis mimicking cutaneous lymphoreticular process.模仿皮肤淋巴网状组织病变的结节性二期梅毒。
J Am Acad Dermatol. 1987 Nov;17(5 Pt 2):914-7. doi: 10.1016/s0190-9622(87)70280-1.
9
Keratopustular variety of framboesiform syphilis: a case report.脓疱型杨梅状梅毒:一例报告
Br J Vener Dis. 1977 Jun;53(3):195-9. doi: 10.1136/sti.53.3.195.
10
Extensive condyloma lata.广泛扁平湿疣
Br J Vener Dis. 1977 Feb;53(1):23-5. doi: 10.1136/sti.53.1.23.