Duke Felicia D, Strong Travis D, Bentley Ellison, Dubielzig Richard R
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive West, Madison, WI 53706, USA.
Vet Ophthalmol. 2013 Jul;16 Suppl 1:188-90. doi: 10.1111/vop.12066. Epub 2013 May 22.
Practitioners approach chemical ciliary body ablation (CBA) in cats with caution. In 1994, an academic letter proposed a potential link between intraocular gentamicin injections for glaucoma and the appearance of ocular tumors in cats (Veterinary and Comparative Ophthalmology, 4, 1994, 166). There is an historic perceived risk for the development of feline ocular post-traumatic sarcoma following gentamicin ciliary body ablation, and many clinicians refrain from chemical ablation in cats for this reason. A recent study discussed the possibility of a correlation between intravitreal gentamicin and tumor promotion in dogs (Veterinary Ophthalmology, 16, 2013, 159). We searched the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database for cases of cats diagnosed with ocular tumors following ciliary body ablation. Of eight cases with historic gentamicin injection, five had malignant tumors: three post-traumatic sarcomas and two melanomas.
从业者在对猫进行化学性睫状体消融术（CBA）时需谨慎。1994年，一封学术信函提出，青光眼眼内注射庆大霉素与猫眼部肿瘤的出现之间可能存在联系（《兽医与比较眼科学》，第4卷，1994年，第166页）。长期以来，人们认为庆大霉素睫状体消融术后猫有发生眼外伤后肉瘤的风险，许多临床医生因此避免对猫进行化学消融。最近一项研究讨论了玻璃体内注射庆大霉素与犬肿瘤促进之间存在关联的可能性（《兽医眼科学》，第16卷，2013年，第159页）。我们在威斯康星比较眼病理实验室（COPLOW）数据库中搜索了睫状体消融术后被诊断患有眼部肿瘤的猫的病例。在有庆大霉素注射史的8例病例中，5例患有恶性肿瘤：3例眼外伤后肉瘤和2例黑色素瘤。
