Schäffer E H, Gordon S
Institut für Pathologie, GSF-Forschungszentrums für Umwelt.
Tierarztl Prax. 1993 Jun;21(3):255-64.
The clinical and pathological findings of 37 feline ocular melanomas are described. The majority of the tumors examined were diffuse iris-ciliary body melanomas of epithelioid and pleomorphic (anaplastic) cell type with numerous mitotic figures. The majority of the tumors showed invasion of the anterior sclera. Metastases were found in three cases predominantly in the abdominal viscera (liver). The clinical diagnostics as well as the differential diagnosis, therapy and prognosis of feline uveal melanoma are presented. The causal pathogenesis is discussed comparatively.
描述了37例猫眼部黑色素瘤的临床和病理表现。所检查的大多数肿瘤为弥漫性虹膜睫状体黑色素瘤,具有上皮样和多形性(间变性)细胞类型,有大量有丝分裂象。大多数肿瘤显示侵犯前巩膜。在3例中发现转移,主要转移至腹腔脏器(肝脏)。介绍了猫葡萄膜黑色素瘤的临床诊断以及鉴别诊断、治疗和预后。对病因发病机制进行了比较讨论。