妊娠期抗磷脂抗体综合征管理中的抗凝治疗
Anticoagulation in management of antiphospholipid antibody syndrome in pregnancy.
作者信息
Lockshin Michael D
机构信息
The Barbara Volcker Center for Women and Rheumatic Disease, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY 10021, USA.
出版信息
Clin Lab Med. 2013 Jun;33(2):367-76. doi: 10.1016/j.cll.2013.01.001. Epub 2013 Apr 19.
Abstract
Knowledge of antiphospholipid antibodies and their impact on pregnancy continues to evolve. A variety of antiphospholipid antibodies have been identified, but not all of them seem to be pathologic for pregnancy outcome. Understanding of which patients are at high risk for adverse pregnancy outcome and the most effective treatment will require clinical trials based on risk stratification and long-term follow-up of infants.
摘要
抗磷脂抗体及其对妊娠影响的相关知识仍在不断发展。已鉴定出多种抗磷脂抗体，但并非所有这些抗体似乎都对妊娠结局具有病理性影响。要了解哪些患者发生不良妊娠结局的风险较高以及最有效的治疗方法，将需要基于风险分层和对婴儿进行长期随访的临床试验。
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