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老年人的甲状腺疾病。

Thyroid disorders in older adults.

机构信息

Thyroid Division, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

Endocrinol Metab Clin North Am. 2013 Jun;42(2):287-303. doi: 10.1016/j.ecl.2013.02.008. Epub 2013 Mar 29.

DOI:10.1016/j.ecl.2013.02.008
PMID:23702402
Abstract

This article summarizes the current literature about serum thyroid parameters and thyroid disease during aging. Changes in thyroid function tests may be part of the physiology of aging, after exclusion of confounding variables. Overt thyroid disease requires immediate treatment. Treatment of subclinical hyperthyroidism in the elderly can be advocated, while watchful waiting may be an appropriate approach for subclinical hypothyroidism.

摘要

本文总结了目前关于血清甲状腺参数和衰老过程中甲状腺疾病的文献。在排除混杂因素后,甲状腺功能试验的变化可能是衰老生理的一部分。显性甲状腺疾病需要立即治疗。老年亚临床甲亢的治疗可以被提倡,而亚临床甲状腺功能减退症的观察等待可能是一种合适的方法。

相似文献

1
Thyroid disorders in older adults.老年人的甲状腺疾病。
Endocrinol Metab Clin North Am. 2013 Jun;42(2):287-303. doi: 10.1016/j.ecl.2013.02.008. Epub 2013 Mar 29.
2
Thyroid disorders during pregnancy.妊娠期甲状腺疾病。
Gynecol Endocrinol. 2012 Dec;28(12):993-8. doi: 10.3109/09513590.2012.692001. Epub 2012 Jun 12.
3
Age and the thyroid.年龄与甲状腺。
Endocrinol Metab Clin North Am. 1987 Dec;16(4):1013-25.
4
Thyroid dysfunction: how to manage overt and subclinical disease in older patients.甲状腺功能障碍:如何管理老年患者的显性和亚临床疾病。
Geriatrics. 1998 Apr;53(4):32-8, 41.
5
[Role of the hypophysis in thyroid pathology].[垂体在甲状腺病理学中的作用]
Schweiz Med Wochenschr. 1968 Feb 3;98(5):148-56.
6
Thyroid physiology in the fetus and newborn: current concepts and approaches to perinatal thyroid disease.胎儿及新生儿的甲状腺生理学:围产期甲状腺疾病的当前概念与处理方法
Prog Clin Biol Res. 1976;10:221-33.
7
The thyroid: recent advances in normal and abnormal physiology.甲状腺:正常与异常生理学的最新进展
Adv Pediatr. 1979;26:441-534.
8
The clinical significance of subclinical thyroid dysfunction.亚临床甲状腺功能障碍的临床意义。
Endocr Rev. 2008 Feb;29(1):76-131. doi: 10.1210/er.2006-0043. Epub 2007 Nov 8.
9
[Thyroid function and dysfunction in the elderly].[老年人的甲状腺功能与功能障碍]
Rev Med Interne. 1996;17(8):653-60. doi: 10.1016/0248-8663(96)87151-7.
10
Diagnosis and management of thyroid disease in pregnancy.妊娠与甲状腺疾病的诊断与管理。
Obstet Gynecol Clin North Am. 2010 Jun;37(2):173-93. doi: 10.1016/j.ogc.2010.02.007.

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Impaired central sensitivity to thyroid hormone is associated with hypertriglyceridemia in euthyroid population.甲状腺功能正常人群中,中枢对甲状腺激素的敏感性受损与高甘油三酯血症有关。
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Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice.由于 DNA 修复缺陷导致的小鼠全身和肝脏特异性而非大脑特异性加速老化,导致肝脏甲状腺激素信号转导降低。
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Mechanistic advances in osteoporosis and anti-osteoporosis therapies.
骨质疏松症及抗骨质疏松症治疗的机制进展
MedComm (2020). 2023 May 11;4(3):e244. doi: 10.1002/mco2.244. eCollection 2023 Jun.
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Association Between Thyroid Dysfunction and Incident Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study.社区动脉粥样硬化风险神经认知研究中甲状腺功能障碍与新发痴呆症之间的关联
J Endocrinol Metab. 2019 Aug;9(4):82-89. doi: 10.14740/jem588.
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Sex Differences in the Associations of Obesity With Hypothyroidism and Thyroid Autoimmunity Among Chinese Adults.中国成年人中肥胖与甲状腺功能减退及甲状腺自身免疫性疾病关联的性别差异
Front Physiol. 2018 Oct 4;9:1397. doi: 10.3389/fphys.2018.01397. eCollection 2018.
6
Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults.治疗后的甲状腺功能减退症与老年人的脑血管疾病有关,但与阿尔茨海默病的病理无关。
Neurobiol Aging. 2018 Feb;62:64-71. doi: 10.1016/j.neurobiolaging.2017.10.004. Epub 2017 Nov 4.
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Ageing Is Associated with Decreases in Appetite and Energy Intake--A Meta-Analysis in Healthy Adults.衰老与食欲和能量摄入的减少相关——一项针对健康成年人的荟萃分析。
Nutrients. 2016 Jan 7;8(1):28. doi: 10.3390/nu8010028.