Endocrine, Bariatric and metabolic Unit, Center of Excellence, General Surgery Department, Universitary Hospital Vall d'Hebron, Passeig de la Vall d'Hebron, 119-129, 08035, Barcelona, Spain.
Endocr Pathol. 2013 Sep;24(3):132-5. doi: 10.1007/s12022-013-9250-2.
Malignant teratoma of the thyroid is a rare and aggressive tumor, frequent in children than in adults. Histologically, thyroid teratomas usually show a predominance of a neuroectodermal component. Mature cartilage and bone may be present. We present the case of primary malignant teratoma of the thyroid in a 64-year-old man. Histologically, the tumor displayed a predominant neuroectodermal component. The diagnosis was confirmed by immunohistochemistry. The patient underwent a radical thyroidectomy with central neck dissection as primary treatment and radioiodine treatment afterwards. The patient had local and distant recurrence. A second surgery was performed with poor results and the patient died 3 months afterwards.
甲状腺恶性畸胎瘤是一种罕见且侵袭性的肿瘤，多见于儿童，少见发生于成人。组织学上，甲状腺畸胎瘤通常以神经外胚层成分为主。成熟的软骨和骨组织可能存在。我们报告一例 64 岁男性的原发性甲状腺恶性畸胎瘤。组织学上，肿瘤以神经外胚层成分为主。免疫组化进一步证实了诊断。患者接受了根治性甲状腺切除术和中央颈淋巴结清扫术作为初始治疗，随后进行了放射性碘治疗。患者出现局部和远处复发。再次手术效果不佳，患者在 3 个月后死亡。
