Buckley N J, Burch W M, Leight G S
Surgery. 1986 Nov;100(5):932-7.
Teratomas in the neck are rare neoplasms. Most occur in the neonate and are benign. In contrast, cervical teratomas in adults are malignant and carry a poor prognosis. Fourteen adult cases have been reported in the world literature, and 11 of these were stated to have arisen in the thyroid gland. A case of a 27-year-old man who presented with a large goiter is reported. A preoperative diagnosis of a malignant thyroid mass was suggested by clinical examination, needle aspiration, and computerized tomography. The patient had a subtotal debulking thyroidectomy. The pathologic specimen confirmed a primary malignant teratoma of the thyroid gland. Despite a combination of radiotherapy and chemotherapy, which were well tolerated, the patient died 2 months after surgery.
颈部畸胎瘤是罕见的肿瘤。大多数发生于新生儿，且为良性。相比之下，成人颈部畸胎瘤为恶性，预后较差。世界文献报道了14例成人病例，其中11例据称起源于甲状腺。本文报道了1例27岁男性患者，其表现为巨大甲状腺肿。临床检查、针吸活检及计算机断层扫描提示术前诊断为甲状腺恶性肿块。患者接受了甲状腺次全切除术。病理标本证实为原发性甲状腺恶性畸胎瘤。尽管患者对放疗和化疗联合治疗耐受性良好，但术后2个月仍死亡。
