Monteiro Lorena Dias, Alencar Carlos Henrique Morais de, Barbosa Jaqueline Caracas, Braga Katiane Pereira, Castro Milene Damous de, Heukelbach Jorg
Universidade Federal do Ceará, Fortaleza, Brasil.
Cad Saude Publica. 2013 May;29(5):909-20.
Chronic sequelae and disabilities are one of the main problems in leprosy. The current study aimed to estimate the prevalence of disabilities in leprosy patients after successfully completing multidrug therapy in Araguaína, Tocantins State, Brazil. This was a cross-sectional study including 282 cases diagnosed from 2004 to 2009. The degrees of disability at diagnosis and at discharge from treatment were collected from medical records and the National Information System for Notifiable Diseases (SINAN). A simplified neurological workup was performed after discharge from treatment. The prevalence of disabilities at diagnosis was 29.4%, and 8.9% of then was grade II. Between diagnosis and discharge, the degree of physical disability worsened in 25% of cases. At diagnosis, the proportion of deformities was significantly higher in men (RR = 1.7; 95%CI: 1.23-2.37). There was a significant association between disability and multibacillary disease (p < 0.001) and occurrence of reactions (p < 0.001). The data show that after discharge from multidrug therapy, in order to prevent chronic sequelae and functional limitations, continuous monitoring is still needed for individuals that have been recorded as cured and thus deleted from the records.
慢性后遗症和残疾是麻风病的主要问题之一。本研究旨在评估巴西托坎廷斯州阿拉瓜伊纳市成功完成多药治疗后的麻风病患者的残疾患病率。这是一项横断面研究,纳入了2004年至2009年诊断的282例病例。从病历和国家法定传染病信息系统(SINAN)收集诊断时和治疗出院时的残疾程度。治疗出院后进行了简化的神经学检查。诊断时的残疾患病率为29.4%,其中8.9%为二级残疾。在诊断和出院之间,25%的病例身体残疾程度恶化。诊断时,男性的畸形比例显著更高(RR = 1.7;95%CI:1.23 - 2.37)。残疾与多菌型疾病(p < 0.001)和反应的发生(p < 0.001)之间存在显著关联。数据表明,在多药治疗出院后,为了预防慢性后遗症和功能受限,对于已记录为治愈并因此从记录中删除的个体仍需要持续监测。