细胞刷在确定宫颈涂片细胞组成方面的作用。
Contribution of the cytobrush to determining cellular composition of cervical smears.
作者信息
Doornewaard H, van der Graaf Y
机构信息
Cyt-U-Universitair, Cytologic Laboratory, State University of Utrecht, The Netherlands.
出版信息
J Clin Pathol. 1990 May;43(5):393-6. doi: 10.1136/jcp.43.5.393.
A study was made of the contribution of the cytobrush to determining the composition of the cervical smear. From a population of women screened in The Netherlands in 1987, 733 women were selected whose smears for the second time in a row lacked endocervical cells. Note was made of method of contraception, age of the woman, and day of the menstrual cycle. A control group was formed of women whose smears contained endocervical cells. Highly significant differences were found in the results between the two groups. Two new samples were collected, one made with the modified wooden Ayre spatula, the other with the cytobrush from the research group. The number of smears containing endocervical cells increased from 44% (by spatula alone) to 79% (spatula plus cytobrush). The cytobrush alone produced a high percentage of unsatisfactory smears (17.5%) due to a low content of squamous epithelial cells. No differences could be observed in the rate of cellular atypia because of the small number of cases.
对细胞刷在确定宫颈涂片成分方面的作用进行了一项研究。从1987年在荷兰接受筛查的女性群体中，挑选出733名女性，她们的涂片连续第二次没有宫颈管内膜细胞。记录了避孕方法、女性年龄和月经周期的日期。由涂片含有宫颈管内膜细胞的女性组成了一个对照组。两组结果之间发现了高度显著的差异。采集了两个新样本，一个用改良的木制艾尔刮板制作，另一个用研究组的细胞刷制作。含有宫颈管内膜细胞的涂片数量从44%（仅用刮板）增加到79%（刮板加细胞刷）。仅使用细胞刷时，由于鳞状上皮细胞含量低，产生了高比例的不合格涂片（17.5%）。由于病例数量少，在细胞异型率方面未观察到差异。
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