Nunes Thiago Franchi, Barbosa Fabio Colagrossi Paes, Miiji Luciana Nakao Odashiro, de Souza Luiz Gustavo Orlandi
Department of Clinical Radiology, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
BMJ Case Rep. 2013 May 22;2013:bcr2013009511. doi: 10.1136/bcr-2013-009511.
Angiosarcoma of the liver is a rare disease; however, it ranks as the third most common primary liver malignancy. Diagnosis is difficult and prognosis is very poor. After the onset of clinical symptoms, the disease often progresses rapidly, decreasing the chances of curative treatment. We report the case of an 83-year-old male patient who presented with postprandial fullness. Upper abdominal ultrasound showed a hypervascular mass in segment 6 of the liver. The results of anatomopathological examination and immunohistochemistry were compatible with the diagnosis of primary angiosarcoma of the liver. Patient refused surgery (haepatectomy), and treatment was then initiated with transarterial chemoembolisation, followed by percutaneous radiofrequency ablation. The patient is currently cured based on clinical and radiological evidence. This case report is the first in the literature to describe the combined use of transarterial chemoembolisation with percutaneous radiofrequency ablation in the treatment of primary angiosarcoma of the liver.
肝血管肉瘤是一种罕见疾病；然而，它是第三常见的原发性肝脏恶性肿瘤。诊断困难且预后很差。临床症状出现后，疾病往往进展迅速，降低了治愈性治疗的机会。我们报告一例83岁男性患者，其表现为餐后饱胀感。上腹部超声显示肝脏第6段有一个高血运肿块。解剖病理学检查和免疫组化结果与原发性肝血管肉瘤的诊断相符。患者拒绝手术（肝切除术），随后开始行经动脉化疗栓塞，接着进行经皮射频消融。根据临床和影像学证据，该患者目前已治愈。本病例报告是文献中首例描述经动脉化疗栓塞与经皮射频消融联合用于治疗原发性肝血管肉瘤的病例。
