Mathewos Biniam, Birhan Wubet, Kinfe Sebesbe, Boru Meaza, Tiruneh Gemechu, Addis Zelalem, Alemu Agersew
Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
BMC Public Health. 2013 May 25;13:508. doi: 10.1186/1471-2458-13-508.
HIV/AIDS infection in health care facility has become a major health problem. Especially in resource poor setting health care workers are managing huge number of HIV infected patients that made them to be more exposed to HIV infection. This situation makes the use of post exposure prophylaxis for HIV very important. Therefore the aim of the study was to assess knowledge, attitude and practice of health care workers towards post exposure prophylaxis for HIV.
Cross-sectional study was conducted among 195 health care workers from February 15 to June 20, 2012. Data was collected using self-administered questionnaire and entered and analyzed using SPSS-20 version. Results were summarized in percentages and presented in tables.
Significant proportions of respondents, 72 (36.9%), were found to have inadequate knowledge about post exposure prophylaxis for HIV. However the majority of respondent 147 (75.4%) had good attitude toward the PEP and significant number of the respondents, 66 (33.8%), had been exposed to blood, body fluids, needles or sharp objects once or more times while giving care for patients. Among these exposed, 49 (74.2%) took PEP but the rest 17 (25.7%) didn't take PEP. From these exposed respondents that took PEP, 23 (46.9%) correctly started taking of PEP at exact initiation time, but the rest started after the recommended initiation time. Among those who took PEP, 39 (79 .6%) completed taking the drug, however 10 (20.4%) didn't complete the PEP regimen.
As a conclusion, significant proportion of study subjects had less knowledge and practice even though the majority of respondents had favorable attitude towards PEP. Therefore, a formal training for all HCWs regarding PEP for HIV and also establishing a 24 hour accessible formal PEP centre with proper guideline is recommended.
医疗机构中的艾滋病毒/艾滋病感染已成为一个主要的健康问题。尤其是在资源匮乏地区，医护人员要管理大量艾滋病毒感染患者，这使他们更容易接触到艾滋病毒感染。这种情况使得艾滋病毒暴露后预防措施的使用变得非常重要。因此，本研究的目的是评估医护人员对艾滋病毒暴露后预防措施的知识、态度和实践情况。
2012年2月15日至6月20日，对195名医护人员进行了横断面研究。使用自填式问卷收集数据，并使用SPSS 20版进行录入和分析。结果以百分比汇总并列于表格中。
发现相当比例的受访者，即72人（36.9%），对艾滋病毒暴露后预防措施的知识不足。然而，大多数受访者147人（75.4%）对暴露后预防措施持良好态度，并且相当数量的受访者，即66人（33.8%），在为患者提供护理时曾接触过血液、体液、针头或锐器一次或多次。在这些接触者中，49人（74.2%）采取了暴露后预防措施，但其余17人（25.7%）未采取暴露后预防措施。在这些采取了暴露后预防措施的接触者中，23人（46.9%）在确切的开始时间正确开始服用暴露后预防药物，但其余人在建议的开始时间之后才开始。在采取了暴露后预防措施的人中，39人（79.6%）完成了药物服用，然而10人（20.4%）未完成暴露后预防方案。
总之，尽管大多数受访者对暴露后预防措施持积极态度，但相当比例的研究对象知识和实践不足。因此，建议为所有医护人员提供关于艾滋病毒暴露后预防措施的正规培训，并建立一个24小时可及的正规暴露后预防中心，并制定适当的指导方针。
