Department of Pharmacognosy, School of Pharmacy Gondar, University of Gondar-College of Medicine and Health Sciences, Gondar, Ethiopia.
Department of Clinical pharmacy, School of Pharmacy Gondar, University of Gondar-College of Medicine and Health Sciences, Gondar, Ethiopia.
BMC Health Serv Res. 2019 Oct 21;19(1):713. doi: 10.1186/s12913-019-4611-2.
HIV/AIDS in resource-limited settings poses a high risk of occupational exposure to healthcare workers due to higher number of HIV infected patients. Hence, antiretroviral based post-exposure prophylaxis (PEP) for HIV is very crucial. The aim of the study was to determine the knowledge, attitudes, and practices of medical and Health science students on antiretroviral based HIV PEP in University of Gondar comprehensive specialized hospital (UOGCSH), Northwestern Ethiopia.
An institutional-based cross-sectional study was conducted among 220 medical and health science graduating students in UOGCSH from May to July 2015. Data were collected using a self-administered pretested questionnaire. The collected data were analyzed using SPSS software version 22. Results were summarized in frequencies, percentages, and means with standard deviations and presented using tables or figures.
Among the respondents, only sixty-six (30%) of the 220 study participants has had adequate knowledge about HIV PEP. Furthermore, over 90 % of the students had positive attitude towards HIV PEP f. Out of the total respondents, 37/220 (16.8%) were in need of HIV PEP and of these students only 18/37 (48.6%) took PEP. On the other hand, merely 50% of the study subjects completed the full course of HIV PEP, while the rest 50% failed to finish. As to the respondents self-report, the sole reason for starting but failing to complete the full course of HIV PEP was intolerance to the side effects of antiretroviral.
Although majority of the respondents had poor knowledge and practice, they owned a good attitude towards HIV PEP. Therefore, a pre-service intensive training for all students regarding HIV PEP prior to their clinical attachments is mandatory. In addition, potential side effects of ARTs and its managements should be priory informed to the students so as to prevent the associated non-adherence to ultimately reduce the incidence of drug resistance. Moreover, the habit of needle stick injury reporting was found to be poor that needs due improvement and there has been also a pressing need to supply sufficient protective barriers to the students while planning and rendering services.
资源有限环境中的艾滋病毒/艾滋病对医护人员构成了很高的职业暴露风险，因为艾滋病毒感染患者数量较多。因此，基于抗逆转录病毒的暴露后预防（PEP）对艾滋病毒非常重要。本研究旨在确定在埃塞俄比亚西北部贡德尔大学综合专科医院（UOGCSH）的医学和卫生科学专业学生对基于抗逆转录病毒的 HIV PEP 的知识、态度和实践。
2015 年 5 月至 7 月，在 UOGCSH 进行了一项基于机构的横断面研究，共有 220 名医学和卫生科学专业的毕业生参加。使用自我管理的预测试问卷收集数据。使用 SPSS 软件版本 22 分析收集的数据。结果以频率、百分比、平均值和标准差进行总结，并以表格或图形呈现。
在受访者中，仅有 220 名研究参与者中的 66 名（30%）对 HIV PEP 有足够的了解。此外，超过 90%的学生对 HIV PEP 持积极态度。在所有受访者中，有 37/220（16.8%）需要进行 HIV PEP，其中只有 18/37（48.6%）接受了 PEP。另一方面，只有 50%的研究对象完成了 HIV PEP 的全部疗程，而其余 50%的人未能完成。就受访者的自我报告而言，开始但未能完成 HIV PEP 全部疗程的唯一原因是无法耐受抗逆转录病毒的副作用。
尽管大多数受访者的知识和实践都很差，但他们对 HIV PEP 的态度良好。因此，在学生临床实习之前，必须对所有学生进行 HIV PEP 的岗前强化培训。此外，应优先向学生告知 ARTs 的潜在副作用及其管理，以防止相关的不依从，最终降低耐药性的发生率。此外，发现针刺伤报告的习惯很差，需要改进，在计划和提供服务时，还迫切需要向学生提供足够的保护屏障。
