Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
J Minim Invasive Gynecol. 2013 Sep-Oct;20(5):637-41. doi: 10.1016/j.jmig.2013.04.005. Epub 2013 May 23.
To evaluate the effects of salpingectomy on the ovarian response to gonadotropins and in vitro fertilization-embryo transfer (IVF-ET) cycle outcomes in women with tubal factor infertility.
A retrospective study (Canadian Task Force Classification II-3) SETTING: An in vitro fertilization laboratory in a university hospital in Taiwan.
We analyzed the outcomes of 288 consecutive fresh IVF-ET cycles in 251 consecutive women with tubal factor infertility from January 2001 to December 2011. Two hundred eighty-eight cycles were divided into 2 groups comprising 103 cycles with laparoscopic salpingectomy and 185 cycles with prior bilateral tubal sterilization, laparoscopic tuboplasty, or proximal tubal occlusion as the control group.
Controlled ovarian hyperstimulation and IVF-ET.
The main outcome was measured by comparing the duration of stimulation, number of gonadotropin ampoules per cycle, number of follicles, number of oocytes retrieved, fertilization rate, implantation rate, clinical pregnancy rate, and live birth rate. We observed no significant difference in any ovarian response parameter between the salpingectomy and nonsalpingectomy groups. Implantation rates, clinical pregnancy rates, and live birth rates were similar. The mean numbers of follicles and oocytes retrieved ipsilateral to the operated side in the salpingectomy group were similar to the numbers of follicles and oocytes retrieved from the nonoperated ovary.
Laparoscopic salpingectomy did not have a negative effect on the ovarian response in women with tubal factor infertility.
评估输卵管因素不孕患者行输卵管切除术对促性腺激素反应和体外受精-胚胎移植（IVF-ET）周期结局的影响。
回顾性研究（加拿大卫生保健研究与发展局分类 II-3 级）。
台湾一所大学医院的体外受精实验室。
我们分析了 2001 年 1 月至 2011 年 12 月 251 例连续输卵管因素不孕患者 288 个新鲜 IVF-ET 周期的结局。288 个周期分为 2 组，103 个周期行腹腔镜输卵管切除术，对照组为 185 个周期行双侧输卵管绝育术、腹腔镜输卵管整形术或近端输卵管阻塞术。
控制性卵巢刺激和 IVF-ET。
主要结局通过比较促性腺激素用量、每个周期的促性腺激素安瓿数、卵泡数、获卵数、受精率、着床率、临床妊娠率和活产率来衡量。我们观察到输卵管切除术组和非输卵管切除术组之间的任何卵巢反应参数均无显著差异。着床率、临床妊娠率和活产率相似。输卵管切除术组手术侧的卵泡和卵母细胞数量与未手术卵巢的卵泡和卵母细胞数量相似。
腹腔镜输卵管切除术对输卵管因素不孕患者的卵巢反应无不良影响。
