Oji Tomito, Sakamoto Yoshiaki, Ogata Hisao, Tamada Ikkei, Kishi Kazuo
Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ward, Tokyo 160-8582, Japan.
Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1183-5. doi: 10.1016/j.ijporl.2013.04.033. Epub 2013 May 21.
To evaluate the effect of diagnostic and operative time on velopharyngeal closure in submucosal cleft palate (SMCP).
SMCP patients treated at the Keio University School of Medicine from 1986 to 2011 were enrolled as subjects. Clinical data were obtained, including patient sex, age at diagnosis, and operative age, occasion of diagnosis, accompanying deformities, speech test results before and 6 months after palatoplasty, and pharyngeal flap usage after palatoplasty.
Data were available for 16 patients, with a mean diagnostic age of 51.1 months (range: 0-132 months). The clinical presentations were bifid uvula in 4 patients and speech dysfunction in 11. The cases suspected from bifid uvula were diagnosed significantly earlier than those with speech dysfunction (19.5 versus 56.8 months, p<0.01). Velopharyngeal closure was improved in 6 cases, and the average age of these patients at surgery was significantly lower than that of the other patients (46.7 versus 79.8 months, p<0.05). A pharyngeal flap was performed in 7 cases (43.8%). The pharyngeal flap usage rate in cleft palate patients other than those with SMCP was significantly lower than that of SMCP patients (3.5% versus 43.8%, p<0.01).
Early discovery and surgical correction is vital for improving postoperative speech outcomes in SMCP patients. This requires educating physicians about SMCP and future studies regarding simple and effective SMCP screening methods.
评估诊断时间和手术时间对黏膜下腭裂(SMCP)患者腭咽闭合的影响。
选取1986年至2011年在庆应义塾大学医学院接受治疗的SMCP患者作为研究对象。收集临床数据,包括患者性别、诊断时年龄、手术年龄、诊断时机、伴随畸形、腭裂修复术前及术后6个月的语音测试结果以及腭裂修复术后咽瓣的使用情况。
16例患者纳入研究,平均诊断年龄为51.1个月(范围:0 - 132个月)。临床表现为4例患者出现双裂悬雍垂,11例患者存在言语功能障碍。双裂悬雍垂疑似病例的诊断时间显著早于言语功能障碍患者(19.5个月对56.8个月,p<0.01)。6例患者的腭咽闭合情况得到改善,这些患者的平均手术年龄显著低于其他患者(46.7个月对79.8个月,p<0.05)。7例患者(43.8%)进行了咽瓣手术。非SMCP腭裂患者的咽瓣使用率显著低于SMCP患者(3.5%对43.8%,p<0.01)。
早期发现和手术矫正对于改善SMCP患者术后语音效果至关重要。这需要对医生进行SMCP相关知识的培训,并开展关于简单有效SMCP筛查方法的进一步研究。