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婴儿期患者的黏膜下腭裂与鼻反流病史之间的关系。

The Relationship between Submucous Cleft Palate and a History of Nasal Regurgitation in Patients during Infancy.

作者信息

Ishigaki Tatsuya, Akita Shinsuke, Udagawa Akikazu, Suzuki Hiroyuki, Mitsukawa Nobuyuki

机构信息

Department of Plastic Surgery, Chiba Children's Hospital, Chiba, Japan.

Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.

出版信息

J Plast Reconstr Surg. 2024 Feb 16;3(3):99-103. doi: 10.53045/jprs.2022-0046. eCollection 2024 Jul 27.

Abstract

OBJECTIVES

Submucous cleft palate is a congenital disorder resulting in velopharyngeal insufficiency. Nasal regurgitation is one of the symptoms of submucous cleft palate. This study aims to investigate a relationship between submucous cleft palate and a history of nasal regurgitation in patients during infancy.

METHODS

This retrospective study includes patients diagnosed with submucous cleft palate at our hospital for 20 years, from 1998 to 2017. Based on the clinical records of these patients, we investigated sex, age at referral to our facility, age at surgery, presence of nasal regurgitation, method of surgery, association of syndromes and mental retardation, and transition of velopharyngeal function.

RESULTS

There were fifty-seven patients referred to our facility. Patients with episodes of nasal regurgitation were referred to clinics later than those without nasal regurgitation. The timing of surgery was also the same. The velopharyngeal function of patients with nasal regurgitation was worse than that of those without nasal regurgitation.

CONCLUSIONS

A history of nasal regurgitation cannot predict submucous cleft palate. However, patients with submucous cleft palate with nasal regurgitation had worse velopharyngeal function than those without nasal regurgitation. An increased understanding of the relationship between submucous cleft palate and nasal regurgitation and further study will predict submucous cleft palate and determine a good timing for surgical interventions.

摘要

目的

黏膜下腭裂是一种导致腭咽功能不全的先天性疾病。鼻反流是黏膜下腭裂的症状之一。本研究旨在调查婴儿期患者黏膜下腭裂与鼻反流病史之间的关系。

方法

这项回顾性研究纳入了1998年至2017年在我院诊断为黏膜下腭裂的患者,为期20年。根据这些患者的临床记录,我们调查了性别、转诊至我院时的年龄、手术时的年龄、鼻反流的存在情况、手术方法、综合征与智力发育迟缓的关联以及腭咽功能的转变。

结果

有57名患者转诊至我院。有鼻反流发作的患者比没有鼻反流的患者转诊至诊所的时间更晚。手术时间也是如此。有鼻反流的患者的腭咽功能比没有鼻反流的患者更差。

结论

鼻反流病史不能预测黏膜下腭裂。然而,有鼻反流的黏膜下腭裂患者的腭咽功能比没有鼻反流的患者更差。对黏膜下腭裂与鼻反流之间关系的进一步了解和深入研究将有助于预测黏膜下腭裂并确定手术干预的最佳时机。

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