Gebesh V V, Mitchenko I K, Semenchenko I G, Topol'nitskiĭ V S, Degtiarenko O M, Bugera D A, Golubchenko A M
Klin Med (Mosk). 1990 Mar;68(3):57-61.
Viral hepatitis B is characterized by pronounced chromatid and chromosome structural defects of peripheral blood T lymphocytes. The chromosome aberrations are longer in hepatitis B than in hepatitis A, in protracted and chronic forms in particular. Excessive circulating immune complexes occur in acute hepatitis. Their concentration is higher in protracted viral hepatitis B. Hemostasis is affected too: the more severe hemostatic abnormality, the more grave the disease. Hemocoagulation alterations are linked with the level of circulating immune complexes.
乙型病毒性肝炎的特征是外周血T淋巴细胞存在明显的染色单体和染色体结构缺陷。乙型肝炎中的染色体畸变比甲型肝炎更长，尤其是在迁延型和慢性型中。急性肝炎会出现过多的循环免疫复合物。在迁延型乙型病毒性肝炎中其浓度更高。止血功能也会受到影响：止血异常越严重，疾病就越严重。血液凝固改变与循环免疫复合物水平有关。
