Ananthaneni Anuradha, Undavalli Suresh Babu
Department of Oral Pathology, St Joseph Dental College, Eluru, Andhra Pradesh, India.
BMJ Case Rep. 2013 May 24;2013:bcr2012007641. doi: 10.1136/bcr-2012-007641.
Salivary gland tumours are rare in children and when they do arise, they preferentially affect major salivary glands with sporadic incidence in minor salivary glands. The mucosa of the cheek is an uncommon site of occurrence for intraoral pleomorphic adenoma and most of these cases have been reported in adults. Histologically, it shows a highly variable morphology because of interplay between epithelial and mesenchymal (myxoid, hyaline, chondroid, osseous) elements which arise from same cell clone, which may be a myoepithelial or ductal reserve cell. Here we report a rare case of juvenile pleomorphic adenoma of the cheek in a 12-year-old girl with a predominant epithelial component histologically. Relevant studies are discussed with a focus on its cytology and cytogenetics.
涎腺肿瘤在儿童中较为罕见，一旦发生，主要累及大涎腺，小涎腺则偶有发病。颊黏膜是口腔多形性腺瘤罕见的发病部位，大多数此类病例报道于成人。从组织学上看，由于上皮和间充质（黏液样、透明样、软骨样、骨样）成分之间的相互作用，其形态高度可变，这些成分源自同一个细胞克隆，该克隆可能是肌上皮细胞或导管储备细胞。在此，我们报告一例12岁女孩颊部罕见的青少年多形性腺瘤，组织学上以主要的上皮成分为特征。文中讨论了相关研究，重点关注其细胞学和细胞遗传学。
