Ellies Maik, Schaffranietz Frank, Arglebe Christian, Laskawi Rainer
Department of Otorhinolaryngology, Head and Neck Surgery, University of Göttingen, Göttingen, Germany.
J Oral Maxillofac Surg. 2006 Jul;64(7):1049-58. doi: 10.1016/j.joms.2006.03.006.
We report on 52 juvenile and adolescent patients with benign and malignant tumors of the salivary glands. Controlled follow-up was carried out to examine outcome and side effects of therapy.
The clinical files of 52 patients were evaluated by computer-based methods. Follow-up was comprised of the findings of our clinic as well as those of the primarily consulted physicians and, if possible, up-to-date examinations in our clinic.
Benign tumors had their highest incidence in puberty and postpuberty. Forty patients (20 girls and 20 boys; 77%) had benign growths and 12 patients (9 girls and 3 boys; 23%) suffered from malignant neoplasms. After surgery for benign tumors we saw no postoperative recurrences in long-term follow-up. In the group of malignant tumors, 8 patients (66.7%) survived their disease in the long-term follow-up.
Salivary gland diseases are rare in childhood and adolescence. Their pattern of incidence differs very much from that of adults. This is particularly true for the malignant parotid tumors that are more frequent in juvenile patients, a fact that has to be considered in diagnosis and therapy.
我们报告了52例患有唾液腺良性和恶性肿瘤的青少年患者。进行了对照随访以检查治疗结果和副作用。
通过计算机辅助方法评估了52例患者的临床档案。随访包括我们诊所的检查结果以及首诊医生的检查结果,如有可能,还包括我们诊所的最新检查。
良性肿瘤在青春期和青春期后发病率最高。40例患者(20名女孩和20名男孩;77%)患有良性肿瘤,12例患者(9名女孩和3名男孩;23%)患有恶性肿瘤。良性肿瘤手术后,长期随访未见术后复发。在恶性肿瘤组中,8例患者(66.7%)在长期随访中存活。
唾液腺疾病在儿童和青少年中较为罕见。其发病率模式与成年人有很大不同。对于青少年患者中更常见的恶性腮腺肿瘤尤其如此,这一事实在诊断和治疗中必须予以考虑。