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台湾地区一例福氏耐格里阿米巴脑膜脑炎致死病例。

A fatal case of Naegleria fowleri meningoencephalitis in Taiwan.

作者信息

Su Mei-Yu, Lee Ming-Shih, Shyu Ling-Yuh, Lin Wei-Chen, Hsiao Pei-Ching, Wang Chi-Ping, Ji Dar-Der, Chen Ke-Min, Lai Shih-Chan

机构信息

Clinical Laboratory, Chung Shan Medical University Hospital, Taichung, Taiwan.

出版信息

Korean J Parasitol. 2013 Apr;51(2):203-6. doi: 10.3347/kjp.2013.51.2.203. Epub 2013 Apr 25.

DOI:10.3347/kjp.2013.51.2.203
PMID:23710088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3662064/
Abstract

After bathing at a hot spring resort, a 75-year-old man presented to the emergency department because of seizure-like attack with loss of conscious. This is the first case of primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri in Taiwan. PAM was diagnosed based on detection of actively motile trophozoites in cerebrospinal fluid using a wet-mount smear and the Liu's stain. The amoebae were further confirmed by PCR and gene sequencing. In spite of administering amphotericin B treatment, the patient died 25 days later.

摘要

一名75岁男性在温泉度假区沐浴后，因出现类似癫痫发作并伴有意识丧失而被送往急诊科。这是台湾首例由福氏耐格里阿米巴引起的原发性阿米巴脑膜脑炎（PAM）。通过湿片涂片和刘氏染色在脑脊液中检测到活动的滋养体，从而诊断为PAM。通过聚合酶链反应（PCR）和基因测序进一步确认了阿米巴。尽管给予了两性霉素B治疗，但患者在25天后死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/0656228cbd08/kjp-51-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/8b2378395663/kjp-51-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/63d05eda2090/kjp-51-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/0656228cbd08/kjp-51-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/8b2378395663/kjp-51-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/63d05eda2090/kjp-51-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25c1/3662064/0656228cbd08/kjp-51-203-g003.jpg

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