Department of Gastroenterology, Children's Medical Center Hospital, Tehran University of Medical Science, Tehran, Iran.
Gut Liver. 2013 May;7(3):278-81. doi: 10.5009/gnl.2013.7.3.278. Epub 2013 Apr 9.
BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD) is common in children. Recurrent exposure to gastric acid in GERD may contribute to tooth erosion.
In this prospective study, 54 GERD patients qualified according to endoscopy, pH-metry, and the GERD questionnaire and 58 healthy controls qualified by the GERD questionnaire were assessed. Two groups underwent dental evaluations for the presence, severity, and patterns of erosion and for the stage of dentition using a Tooth Wear Index. The health care providers who performed the dental exams did not know which children had been diagnosed with GERD.
A total of 112 children, 3 to 12 years old were enrolled in the study, and 53 of 54 (98.1%) GERD patients and 11 of 58 (19.0%) controls had dental erosions (p<0.0001). In GERD patients, the posterior occlusal surfaces of milk teeth were more affected (p<0.0001). There was no correlation between GERD and the affected surfaces in permanent teeth, nor in the patterns or erosion grades (localized or general). In both groups, milk teeth had more erosions than permanent teeth, but the difference was not statistically significant.
According to this study, there is a positive correlation between GERD and dental erosion. Posterior occlusal surface erosions in milk teeth could indicate GERD.
背景/目的：胃食管反流病（GERD）在儿童中很常见。GERD 中胃酸的反复暴露可能导致牙齿侵蚀。
在这项前瞻性研究中，根据内镜、pH 监测和 GERD 问卷，符合 GERD 标准的 54 名 GERD 患者和符合 GERD 问卷的 58 名健康对照者符合条件。两组均进行了牙齿评估，以评估有无侵蚀、侵蚀的严重程度和模式以及使用牙齿磨损指数评估牙列的阶段。进行牙科检查的医护人员不知道哪些儿童被诊断为 GERD。
共有 112 名 3 至 12 岁的儿童入组本研究，54 名 GERD 患者中有 53 名（98.1%）和 58 名对照者中有 11 名（19.0%）患有牙齿侵蚀（p<0.0001）。在 GERD 患者中，乳牙的后牙合面受影响更严重（p<0.0001）。GERD 与恒牙的受累面、模式或侵蚀程度（局限性或广泛性）之间无相关性。在两组中，乳牙的侵蚀比恒牙多，但差异无统计学意义。
根据这项研究，GERD 与牙齿侵蚀之间存在正相关。乳牙后牙合面的侵蚀可能提示 GERD。
