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子宫内膜间质增生:一种未得到充分认识的病症。

Endometrial stromal hyperplasia: an underrecognized condition.

作者信息

Sivridis Efthimios, Koutsougeras Gerasimos, Giatromanolaki Alexandra

机构信息

Department of Pathology, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, Greece.

出版信息

Case Rep Pathol. 2013;2013:204082. doi: 10.1155/2013/204082. Epub 2013 Apr 4.

DOI:10.1155/2013/204082
PMID:23710401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3657462/
Abstract

Hyperplasia of the endometrial stroma is a poorly recognized lesion, lacking widespread recognition with most, if not all, such cases sequestrated in the literature as endometrial stromal nodules or low-grade endometrial stromal sarcomas. In this paper, we describe three examples of "endometrial stromal hyperplasia" which have a remarkable morphological similarity with the normally proliferating endometrial stroma and the endometrial stromal neoplasms, but which also possess subtle, but sufficient, differences to justify their taxonomic separation.

摘要

子宫内膜间质增生是一种鲜为人知的病变,并未得到广泛认可,大多数(即便不是全部)此类病例在文献中被归类为子宫内膜间质结节或低级别子宫内膜间质肉瘤。在本文中,我们描述了三例“子宫内膜间质增生”,它们在形态上与正常增殖的子宫内膜间质及子宫内膜间质肿瘤有着显著的相似性,但也存在细微却足以证明其分类区别的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1a6/3657462/53a4c8ee6967/CRIM.PATHOLOGY2013-204082.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1a6/3657462/53a4c8ee6967/CRIM.PATHOLOGY2013-204082.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1a6/3657462/53a4c8ee6967/CRIM.PATHOLOGY2013-204082.001.jpg

相似文献

1
Endometrial stromal hyperplasia: an underrecognized condition.子宫内膜间质增生:一种未得到充分认识的病症。
Case Rep Pathol. 2013;2013:204082. doi: 10.1155/2013/204082. Epub 2013 Apr 4.
2
Effects of hormone therapy on the endometrium.激素疗法对子宫内膜的影响。
Mod Pathol. 1993 Jan;6(1):94-106.
3
CD10 is a sensitive and diagnostically useful immunohistochemical marker of normal endometrial stroma and of endometrial stromal neoplasms.CD10是正常子宫内膜间质及子宫内膜间质肿瘤敏感且具有诊断价值的免疫组化标志物。
Histopathology. 2001 Sep;39(3):273-8. doi: 10.1046/j.1365-2559.2001.01215.x.
4
Endometrial stromal tumors: an update on a group of tumors with a protean phenotype.子宫内膜间质肿瘤:一组具有多变表型的肿瘤的最新进展
Adv Anat Pathol. 2000 Sep;7(5):257-81. doi: 10.1097/00125480-200007050-00001.
5
Endometrial stromal sarcoma of uterus.子宫子宫内膜间质肉瘤。
Best Pract Res Clin Obstet Gynaecol. 2011 Dec;25(6):719-32. doi: 10.1016/j.bpobgyn.2011.07.004. Epub 2011 Aug 6.
6
Undifferentiated Uterine Sarcomas Represent Under-Recognized High-grade Endometrial Stromal Sarcomas.未分化子宫肉瘤代表认识不足的高级子宫内膜间质肉瘤。
Am J Surg Pathol. 2019 May;43(5):662-669. doi: 10.1097/PAS.0000000000001215.
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Endometrial stromal sarcomas and related neoplasms: new developments and diagnostic considerations.子宫内膜间质肉瘤及相关肿瘤:新进展与诊断要点。
Pathology. 2018 Feb;50(2):162-177. doi: 10.1016/j.pathol.2017.11.086. Epub 2017 Dec 22.
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Endometrial stromal sarcoma expression of estrogen receptors, progesterone receptors and estrogen-induced srp27 (24K) suggests hormone responsiveness.子宫内膜间质肉瘤中雌激素受体、孕激素受体及雌激素诱导的srp27(24K)的表达提示其对激素有反应性。
J Steroid Biochem Mol Biol. 1992 Mar;41(3-8):589-96. doi: 10.1016/0960-0760(92)90389-z.
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Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.金属蛋白酶在子宫内膜间质肉瘤中的表达:采用图像分析的免疫组织化学研究
J Clin Pathol. 1999 Mar;52(3):198-202. doi: 10.1136/jcp.52.3.198.
10
Allelic imbalances in endometrial stromal neoplasms: frequent genetic alterations in the nontumorous normal-appearing endometrial and myometrial tissues.子宫内膜间质肿瘤中的等位基因失衡:在外观正常的非肿瘤性子宫内膜和肌层组织中频繁发生的基因改变。
Gynecol Oncol. 2004 Dec;95(3):662-71. doi: 10.1016/j.ygyno.2004.08.016.

本文引用的文献

1
Cytogenetic and molecular aberrations in endometrial stromal tumors.子宫内膜间质肿瘤的细胞遗传学和分子异常。
Hum Pathol. 2011 May;42(5):609-17. doi: 10.1016/j.humpath.2010.12.005. Epub 2011 Mar 21.
2
Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium.子宫内膜上皮性、间质性及混合性肿瘤中的分子遗传学改变。
Pathology. 2007 Feb;39(1):46-54. doi: 10.1080/00313020601146822.
3
Focal endometrial stromal hyperplasia.局灶性子宫内膜间质增生
Histopathology. 1998 Jul;33(1):75-9. doi: 10.1046/j.1365-2559.1998.00458.x.
4
Endometrial polyps with predominant stromal component are characterized by a t(6;14)(p21;q24) translocation.以基质成分为主的子宫内膜息肉具有t(6;14)(p21;q24)易位的特征。
Cancer Res. 1995 Jan 1;55(1):31-3.
5
Mesenchymal tumours of the uterus. VII. A clinicopathological study of 60 endometrial stromal nodules.子宫间叶性肿瘤。VII. 60例子宫内膜间质结节的临床病理研究
Histopathology. 1981 Jan;5(1):1-10. doi: 10.1111/j.1365-2559.1981.tb01761.x.