Vanni R, Marras S, Andria M, Faa G
Istituto di Biologia Generale, Cagliari (Sardinia), Italy.
Cancer Res. 1995 Jan 1;55(1):31-3.
Cytogenetic investigation of endometrial polyps revealed the presence of a t(6;14)(p21;q24) as the sole abnormality in three cases. All tumors showed a histopathological pattern of predominant stromal hyperplasia with scarce representation of glandular elements, suggesting that a cytogenetic subgroup characterized by the t(6;14) translocation can be associated with endometrial polyps with a preponderant component of mesenchymal origin.
子宫内膜息肉的细胞遗传学研究显示，3例患者中均存在t(6;14)(p21;q24)作为唯一异常。所有肿瘤均表现出以间质增生为主、腺性成分稀少的组织病理学模式，提示以t(6;14)易位为特征的细胞遗传学亚组可能与间充质来源占优势的子宫内膜息肉相关。
