以基质成分为主的子宫内膜息肉具有t(6;14)(p21;q24)易位的特征。
Endometrial polyps with predominant stromal component are characterized by a t(6;14)(p21;q24) translocation.
作者信息
Vanni R, Marras S, Andria M, Faa G
机构信息
Istituto di Biologia Generale, Cagliari (Sardinia), Italy.
出版信息
Cancer Res. 1995 Jan 1;55(1):31-3.
PMID:7805036
Abstract
Cytogenetic investigation of endometrial polyps revealed the presence of a t(6;14)(p21;q24) as the sole abnormality in three cases. All tumors showed a histopathological pattern of predominant stromal hyperplasia with scarce representation of glandular elements, suggesting that a cytogenetic subgroup characterized by the t(6;14) translocation can be associated with endometrial polyps with a preponderant component of mesenchymal origin.
摘要
子宫内膜息肉的细胞遗传学研究显示，3例患者中均存在t(6;14)(p21;q24)作为唯一异常。所有肿瘤均表现出以间质增生为主、腺性成分稀少的组织病理学模式，提示以t(6;14)易位为特征的细胞遗传学亚组可能与间充质来源占优势的子宫内膜息肉相关。
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