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[L-精氨酸在子痫前期的防治中]

[L-arginin in prevention and treatment of pre-eclampsia].

作者信息

Vacula L

机构信息

Gynekologicko-Porodnické Oddĕrízská Nemocnice, a.s, Kromĕríz, Primár MUDr. J. Pribik.

出版信息

Ceska Gynekol. 2013 Apr;78(2):181-6.

PMID:23710983
Abstract

OBJECTIVE

It is to show the possible relationship between the patofysiology of pre-eclampsia in the body of a human with a relative lack of L-arginine and its potential connection with a nitrogen metabolism. This study also suggests the further utilization of above mentioned knowledges in a prevention and a treatment of pre-eclampsia.

DESIGN

Literary overview.

SETTING

Gynaecology and Obstetric Department of the Hospital Kromeriz, Inc., Kromeriz.

METHODS

The background research of studies and issues published already in medical professional journals, bulletins and medical web databases.

CONCLUSION

To provide L-arginine to pregnant women as a dietary supplement concerns no risk and is an easy precaution. L-arginine can reduce the occurrance of pre-eclampsia in women with a potential high risk of its development. The most important transmitter substance that makes L-arginine work is the dioxide nitrogen. So far, it has been the outmost possibility how to influence the patofysiology of Pre-eclampsia The lack of L-arginine and its influence on the nitrogen metabolism is likely, but there is also a great need for further research.

摘要

目的

展示人体内相对缺乏L-精氨酸时子痫前期的病理生理学与氮代谢之间可能存在的关系。本研究还建议将上述知识进一步用于子痫前期的预防和治疗。

设计

文献综述。

地点

捷克共和国克罗梅日什市克罗梅日什医院妇产科。

方法

对医学专业期刊、公告及医学网络数据库中已发表的研究和问题进行背景研究。

结论

作为膳食补充剂为孕妇提供L-精氨酸无风险且是一种简便的预防措施。L-精氨酸可降低有子痫前期发生高风险女性的子痫前期发生率。使L-精氨酸发挥作用的最重要递质是二氧化氮。到目前为止,这是影响子痫前期病理生理学的最大可能性。L-精氨酸缺乏及其对氮代谢的影响是有可能的,但也非常需要进一步研究。

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1
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Ceska Gynekol. 2013 Apr;78(2):181-6.
2
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