Child Health Research Unit, Barwon Health, Geelong, Australia.
Clin Exp Allergy. 2013 Jun;43(6):599-607. doi: 10.1111/cea.12048.
A variety of hypotheses have been proposed to explain the recently described increase in food allergy among children living in developed countries. In this study, we summarize the emerging risk factors for IgE-mediated food allergy in early life, and then review the evidence for and against an association between low vitamin status (VDS) and food allergy. We consider whether each of the epidemiological variables that have been associated with food allergy may also be associated with VDS; and argue that future studies must adequately account for the potential relationships between risk factors for food allergy and VDS, and must also discriminate between vitamin D derived by sun exposure, diet and oral supplementation.
多种假说被提出来解释发达国家儿童食物过敏的最近增加。在这项研究中，我们总结了在生命早期 IgE 介导的食物过敏的新兴危险因素，然后回顾了低维生素状态（VDS）与食物过敏之间的关联的证据。我们考虑了与食物过敏相关的每一个流行病学变量是否也与 VDS 相关；并认为未来的研究必须充分考虑食物过敏和 VDS 的危险因素之间的潜在关系，并且还必须区分阳光暴露、饮食和口服补充的维生素 D。
