Department of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering, Delft University of Technology, Delft, The Netherlands.
Ultrasound Med Biol. 2013 Aug;39(8):1368-75. doi: 10.1016/j.ultrasmedbio.2013.02.011. Epub 2013 May 24.
The long-term prognosis of cartilage lesions evolving into an eroding subchondral bone defect is not known. Longitudinal monitoring using ultrasound could assist in overall understanding. The aim of the work described in this article was to determine the feasibility of using ultrasound to detect small (osteo)chondral defects. On the anterior talar surface of 10 human cadaveric ankles, at most four defects were arthroscopically created: two pure chondral defects 3 and 1.5 mm in diameter and two osteochondral defects 3 and 1.5 mm in diameter. All ankles were examined by two observers, and their ultrasound observations were validated using computed tomography scans and photographs. Overall sensitivity was 96% for observer 1 and 92% for observer 2, and specificity for both observers was 100%. Sixty-eight percent and 79% of defect sizes were within relevant limits of agreement (-0.2 ± 1.0 mm), respectively. Ultrasound imaging has the potential to detect small (osteo)chondral defects located within visible areas.
软骨病变进展为侵蚀性软骨下骨缺损的长期预后尚不清楚。使用超声进行纵向监测有助于全面了解。本文所述工作的目的是确定使用超声检测小（骨）软骨缺损的可行性。在 10 个人体尸体踝关节的前距骨表面，最多可通过关节镜创建四个缺损：两个直径为 3 和 1.5 毫米的纯软骨缺损，以及两个直径为 3 和 1.5 毫米的骨软骨缺损。两名观察者检查了所有踝关节，并使用计算机断层扫描和照片验证了他们的超声观察结果。观察者 1 的总体敏感性为 96%，观察者 2 的总体敏感性为 92%，两名观察者的特异性均为 100%。分别有 68%和 79%的缺损尺寸在相关的一致性范围内（-0.2 ± 1.0 毫米）。超声成像有可能检测到位于可见区域内的小（骨）软骨缺损。
