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女性“正常”液体潴留与特发性水肿之间的关系。

The relationship between 'normal' fluid retention in women and idiopathic oedema.

作者信息

Denning D W, Dunnigan M G, Tillman J, Davis J A, Forrest C A

机构信息

Department of Medicine, Stobhill General Hospital, Glasgow, Scotland, UK.

出版信息

Postgrad Med J. 1990 May;66(775):363-6. doi: 10.1136/pgmj.66.775.363.

DOI:10.1136/pgmj.66.775.363
PMID:2371185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2426830/
Abstract

A sample of women attending a gynaecological outpatient clinic were examined for symptoms and objective signs of fluid retention. Patients completed a questionnaire on symptoms suggesting fluid retention and recorded daily weight and abdominal girth variation. Daily weight variation varied from 0-9 pounds (mode 2 pounds) with no discernable difference between premenstrual and intermenstrual variation. Daily girth variation varied from 0-6 inches (mode 1 inch). Symptoms of breast swelling were more common premenstrually, finger/hand and ankle swelling intermenstrually and abdominal swelling occurred with equal frequency in both periods. No correlation between symptoms and weight variation was seen although abdominal swelling and girth variation were associated (P less than 0.04). The results indicate that symptoms of mild fluid retention and of diurnal weight and abdominal girth variation are part of the everyday experience of our study population. There is no clear-cut separation between 'normal' and 'abnormal' fluid retention (idiopathic oedema, periodic oedema, fluid retention syndrome); the latter may be an exaggeration of normal fluid-retaining mechanisms common to most women or may represent a pathological state. An approach which evaluates individual risk factors and the severity of fluid retention in each patient is recommended.

摘要

对在妇科门诊就诊的一组女性进行了液体潴留症状和客观体征检查。患者完成了一份关于提示液体潴留症状的问卷,并记录了每日体重和腹围变化。每日体重变化范围为0至9磅(众数为2磅),经前和经间期变化无明显差异。每日腹围变化范围为0至6英寸(众数为1英寸)。乳房胀痛症状在经前更常见,手指/手部和脚踝肿胀在经间期更常见,腹部肿胀在两个时期出现的频率相同。尽管腹部肿胀与腹围变化相关(P小于0.04),但未发现症状与体重变化之间存在关联。结果表明,轻度液体潴留症状以及每日体重和腹围变化是我们研究人群日常经历的一部分。“正常”和“异常”液体潴留(特发性水肿、周期性水肿、液体潴留综合征)之间没有明确界限;后者可能是大多数女性常见的正常液体潴留机制的过度表现,也可能代表一种病理状态。建议采用一种评估个体风险因素和每位患者液体潴留严重程度的方法。

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本文引用的文献

1
Altered dopaminergic modulation of sympathetic nervous system activity in idiopathic edema.特发性水肿中交感神经系统活动的多巴胺能调节改变
J Endocrinol Invest. 1984 Oct;7(5):461-6. doi: 10.1007/BF03348451.
2
Approach to the patient with "idiopathic edema" or "periodic swelling".“特发性水肿”或“周期性肿胀”患者的诊疗方法。
JAMA. 1968 Oct 7;206(2):333-8.
3
A psychiatric study of idiopathic oedema.特发性水肿的精神病学研究。
Lancet. 1986 Nov 1;2(8514):999-1002. doi: 10.1016/s0140-6736(86)92613-9.
4
Idiopathic oedema of women. A clinical and investigative study.
Q J Med. 1976 Jan;45(177):125-44.
5
Idiopathic edema: pathogenesis, clinical features, and treatment.特发性水肿:发病机制、临床特征及治疗
Metabolism. 1978 Mar;27(3):353-83. doi: 10.1016/0026-0495(78)90115-4.
6
Is "idiopathic" edema idiopathic?“特发性”水肿是特发性的吗?
Lancet. 1979 Feb 24;1(8113):397-400. doi: 10.1016/s0140-6736(79)90880-8.