Grant R, Condon B, Lawrence A, Hadley D M, Patterson J, Bone I, Teasdale G M
Magnetic Resonance Imaging Unit, Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland.
J Comput Assist Tomogr. 1988 Jan-Feb;12(1):36-9. doi: 10.1097/00004728-198801000-00005.
We used magnetic resonance to investigate the hypothesis that premenstrual neurological symptoms are due to cerebral oedema and brain swelling. Total cranial and lateral ventricular CSF volumes were measured midcycle and premenstrually in 20 women with a normal menstrual cycle, and similar measurements were made 2 weeks apart in 10 postmenopausal women and 10 men. Total cranial CSF volume increased premenstrually in 19 women. The mean premenstrual increase was by 11.5 ml. There was not a significant difference between those women who were taking an oral contraceptive and those who were not. The CSF volume did not change significantly on repeat measurement in men and postmenopausal women. The CSF changes observed reflect a reduction in brain volume and do not support cerebral swelling as the cause of premenstrual neurological symptoms.
我们使用磁共振来研究经前神经症状是由脑水肿和脑肿胀引起的这一假设。在20名月经周期正常的女性的月经周期中期和经前期测量了全颅和侧脑室脑脊液体积，在10名绝经后女性和10名男性中每隔2周进行了类似测量。19名女性的全颅脑脊液体积在经前期增加。经前期平均增加11.5毫升。服用口服避孕药的女性和未服用口服避孕药的女性之间没有显著差异。男性和绝经后女性重复测量时脑脊液体积没有显著变化。观察到的脑脊液变化反映了脑容量的减少，不支持脑肿胀是经前神经症状的原因。
