血清素转运体的基因缺失极大地增强了摇头丸对大鼠的强化作用。 - Suppr

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超能文献

A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats.

作者信息

Oakly A C, Brox B W, Schenk S, Ellenbroek B A

机构信息

School of Psychology, Victoria University of Wellington, Wellington, New Zealand.

出版信息

Mol Psychiatry. 2014 May;19(5):534-5. doi: 10.1038/mp.2013.75. Epub 2013 May 28.

DOI:10.1038/mp.2013.75

PMID:23711978

Abstract

摘要

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In vivo effects of amphetamine analogs reveal evidence for serotonergic inhibition of mesolimbic dopamine transmission in the rat.安非他命类似物的体内效应揭示了 5-羟色胺能抑制大鼠中脑边缘多巴胺传递的证据。

J Pharmacol Exp Ther. 2011 Apr;337(1):218-25. doi: 10.1124/jpet.110.176271. Epub 2011 Jan 12.

MDMA ("ecstasy") abuse as an example of dopamine neuroplasticity.以 MDMA（“摇头丸”）滥用为例探讨多巴胺神经可塑性。

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Effect of D1-like and D2-like receptor antagonists on methamphetamine and 3,4-methylenedioxymethamphetamine self-administration in rats.D1样和D2样受体拮抗剂对大鼠甲基苯丙胺和3,4-亚甲基二氧甲基苯丙胺自我给药的影响。

Behav Pharmacol. 2009 Dec;20(8):688-94. doi: 10.1097/FBP.0b013e328333a28d.

5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study.5-HTTLPR 多态性、心境障碍与 3 年随访研究中的 MDMA 使用情况。

Addict Biol. 2010 Jan;15(1):15-22. doi: 10.1111/j.1369-1600.2009.00180.x.

Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system.血清素转运体基因敲除大鼠的特征：血清素能系统功能的选择性变化。

Neuroscience. 2007 Jun 8;146(4):1662-76. doi: 10.1016/j.neuroscience.2007.03.030. Epub 2007 Apr 30.

3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice.在血清素转运体基因敲除小鼠中，3,4-亚甲基二氧甲基苯丙胺的自我给药行为被消除。

Biol Psychiatry. 2007 Sep 15;62(6):669-79. doi: 10.1016/j.biopsych.2006.11.005. Epub 2007 Feb 16.

The effect of polymorphism at the serotonin transporter gene on decision-making, memory and executive function in ecstasy users and controls.5-羟色胺转运体基因多态性对摇头丸使用者及对照组决策、记忆和执行功能的影响。

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Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs.人类和小鼠单胺转运体对精神刺激药物敏感性的比较。

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