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尤特皮(Euterpe edulis)的毒理学评价:一种值得考虑的潜在超级水果。

Toxicological evaluation of Euterpe edulis: a potential superfruit to be considered.

机构信息

Departamento de Biofísica e iometria, Universidade do Estado do Rio de Janeiro, 20551-013 Rio de Janeiro, Brazil.

出版信息

Food Chem Toxicol. 2013 Aug;58:536-44. doi: 10.1016/j.fct.2013.05.029. Epub 2013 May 24.

DOI:10.1016/j.fct.2013.05.029
PMID:23712094
Abstract

Superfruits have a high nutritional value due to their richness in nutrients, antioxidants, proven or potential health benefits and taste appeal. However, there are no scientific criteria for defining which fruits are superfruits. In Brazil, several palms have an edible palm heart, the best known and most widely appreciated of which is called Acai (Euterpe oleracea). Euterpe edulis Mart., commonly called jussara, is an evergreen species that grows in the rainforest. Having initially been consumed in the form of juice and pulp, they have since been incorporated as an ingredient in many foods. A risk assessment to identify adverse health effects is a prerequisite for taking forward the development of new drugs, cosmetics and foods. To make a toxicological evaluation of E. edulis, in the present work this prerequisite was met by an interdisciplinary network that performed mass spectroscopy analyses, blood biochemistry, genotoxicity, bacterial reverse mutation and cytotoxicity assays. Positive mutagenicity results were detected for Salmonella typhimurium TA97 at low doses, and positive results were also obtained for the mammalian erythrocyte micronucleus assay, indicating that the pulp of E. edulis contains compounds with the capacity to induce mutagenicity and clastogenic/aneugenic effects.

摘要

超级水果因其富含营养物质、抗氧化剂、已被证实或潜在的健康益处以及口感吸引力而具有很高的营养价值。然而,目前还没有科学的标准来定义哪些水果是超级水果。在巴西,有几种棕榈树的可食用棕榈心,其中最著名和最受欢迎的是被称为 Acai(Euterpe oleracea)的棕榈心。Euterpe edulis Mart.,通常被称为 jussara,是一种常绿物种,生长在热带雨林中。最初以果汁和果肉的形式被食用,后来被添加到许多食品中。为了识别不良健康影响的风险,需要进行风险评估,这是开发新药、化妆品和食品的前提。为了对 E. edulis 进行毒理学评估,在本工作中,通过一个进行质谱分析、血液生化、遗传毒性、细菌回复突变和细胞毒性测定的跨学科网络,满足了这一前提条件。在低剂量下,沙门氏菌 TA97 检测到阳性致突变性结果,哺乳动物红细胞微核试验也得到阳性结果,表明 E. edulis 的果肉含有具有致突变性和断裂/致畸性作用的化合物。

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