Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Dement Geriatr Cogn Disord. 2013;36(1-2):36-42. doi: 10.1159/000350035. Epub 2013 May 23.
BACKGROUND/AIMS: Even mild stroke survivors may sometimes experience residual cognitive damage. No consensus has emerged about which cognitive test is most appropriate for the diagnosis of poststroke cognitive impairment. We aim to compare a computerized battery of neuropsychological tests for memory, attention and executive functions (MindStreams®) with the Montreal Cognitive Assessment (MoCA) to detect mild-to-moderate cognitive impairments in poststroke patients.
Subjects enrolled to the TABASCO (Tel Aviv Brain Acute Stroke Cohort) study, a prospective study which includes consecutive first-ever mild-to-moderate stroke patients, were included. All participants underwent neurological and cognitive evaluations.
A total of 454 patients with transient ischemic attack (TIA) or stroke are reported. Their mean MoCA and MindStreams scores were lower than normal; however, the TIA group presented significantly better scores using either method. The correlation between the MoCA and the computerized global score was 0.6 (p < 0.001). A significant correlation was found between the subcategory scores (executive function, memory and attention). However, the MoCA identified many more subjects with low scores (<26) compared to the MindStreams (70.6 vs. 15.7%).
Our results demonstrate that either of the modalities alone is sensitive enough for identifying subtle cognitive impairment and none picks up substantially more cognitive losses than the other in patients with cerebrovascular disease.
背景/目的:即使是轻度中风幸存者有时也会经历认知损伤的残留。目前尚未就哪种认知测试最适合诊断中风后认知障碍达成共识。我们旨在比较用于记忆、注意力和执行功能的计算机化神经心理测试组合(MindStreams®)与蒙特利尔认知评估(MoCA),以检测中风后患者的轻度至中度认知障碍。
本研究纳入了参加 TABASCO(特拉维夫急性脑卒中队列)研究的受试者,这是一项包括连续首次轻度至中度中风患者的前瞻性研究。所有参与者均接受了神经学和认知评估。
共报告了 454 例短暂性脑缺血发作(TIA)或中风患者。他们的 MoCA 和 MindStreams 评分均低于正常值;然而,使用任何一种方法,TIA 组的得分都明显更好。MoCA 与计算机化总体评分之间的相关性为 0.6(p < 0.001)。在子类别评分(执行功能、记忆和注意力)之间发现了显著的相关性。然而,与 MindStreams 相比,MoCA 识别出更多得分较低(<26)的受试者(70.6%比 15.7%)。
我们的结果表明,单独使用任何一种方法都足以识别出细微的认知障碍,并且在脑血管疾病患者中,任何一种方法都不会比另一种方法更能检测到更多的认知损失。