在同一骨架上，通过额外的 Watson-Crick 碱基对延伸 DNA 双螺旋。
The extension of a DNA double helix by an additional Watson-Crick base pair on the same backbone.
机构信息
Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, 5230 Odense M, Denmark.
出版信息
Chembiochem. 2013 Jun 17;14(9):1072-4. doi: 10.1002/cbic.201300086. Epub 2013 May 24.
PMID:23712945
Abstract
Additional base pair: The DNA duplex can be extended with an additional Watson-Crick base pair on the same backbone by the use of double-headed nucleotides. These also work as compressed dinucleotides and form two base pairs with cognate nucleobases on the opposite strand.
摘要
额外碱基对
通过使用双头核苷酸，DNA 双螺旋可以在同一骨架上进一步延伸一个额外的 Watson-Crick 碱基对。这些核苷酸也可以作为压缩的二核苷酸，与相反链上的互补碱基形成两个碱基对。
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