Suppr超能文献

脂肪功能障碍指标作为心脏代谢风险评估的关键——一项基于人群的心肌梗死后患者研究

Adipose Dysfunction Indices as a Key to Cardiometabolic Risk Assessment-A Population-Based Study of Post-Myocardial Infarction Patients.

作者信息

Szczepańska Elżbieta, Słoma-Krześlak Małgorzata, Białek-Dratwa Agnieszka, Dudzik Izabela, Kowalski Oskar

机构信息

Department of Human Nutrition, Department of Dietetics, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, ul. Jordana 19, 41-808 Zabrze, Poland.

Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Center for Heart Diseases, ul. Marii Curie-Skłodowskiej 9, 41-800 Zabrze, Poland.

出版信息

Metabolites. 2024 May 24;14(6):299. doi: 10.3390/metabo14060299.

Abstract

Anthropometric indices, such as the BMI (body mass index), WC (waist circumference), and WHR (waist-hip ratio) are commonly used for cardiometabolic risk assessment. Consequently, in the context of evaluating cardiometabolic risk in the post-MI population, it is worthwhile to consider indices such as the Visceral Adiposity Index (VAI) and Body Adiposity Index (BAI), which have emerged as valuable risk assessment tools in clinical trials. The aim of this study was to provide a more comprehensive understanding of the importance of anthropometric indices and body composition analysis in evaluating the cardiometabolic risk among post-myocardial infarction patients. In the pursuit of this objective, this study involved assessing the BMI, WC, WHR, WHtR, VAI, BAI, and body composition in a population of patients. This study enrolled a total of 120 patients hospitalised at the Silesian Centre for Heart Diseases (SCCS) due to MI, and body composition analysis evaluated various parameters including the percentage of adipose tissue (FatP) [%], total adipose tissue (FatM) [kg], fat-free mass (FFM) [kg], muscle mass (PMM) [kg], total body water (TBW) [kg], and visceral adipose tissue (VFAT). The mean BMI for the entire group was 27.76 ± 4.08, with women exhibiting a significantly lower value compared with men (26.66 ± 3.33 vs. 28.16 ± 4.27). The mean values obtained for the WHR, WHtR, BAI, and VAI were 0.97 ± 0.08, 0.59 ± 0.07, 28.37 ± 5.03, and 3.08 ± 3.50, respectively. Based on the visceral adiposity index (VAI), in 47.5% patients, there was no adipose tissue dysfunction, with a higher proportion among women (71.88%) compared with men (38.64%). What raises concern is that 32.50% of patients had acute ATD, with a significantly higher prevalence among men (38.64%) compared with women (15.63%). Conclusion: The study results suggest that the BMI, WC, and WHR have their limitations, whereas the WHtR, VAI, and BAI provide a more comprehensive view of cardiometabolic risk, especially in the context of adipose tissue distribution and its metabolic consequences. Incorporating the WHtR, VAI, and BAI into routine clinical practice may enhance the management of cardiometabolic risk, especially among post-MI patients.

摘要

人体测量指标,如体重指数(BMI)、腰围(WC)和腰臀比(WHR),常用于心脏代谢风险评估。因此,在评估心肌梗死后人群的心脏代谢风险时,考虑诸如内脏脂肪指数(VAI)和身体脂肪指数(BAI)等指标是值得的,这些指标在临床试验中已成为有价值的风险评估工具。本研究的目的是更全面地了解人体测量指标和身体成分分析在评估心肌梗死后患者心脏代谢风险中的重要性。为实现这一目标,本研究对一组患者的BMI、WC、WHR、腰高比(WHtR)、VAI、BAI和身体成分进行了评估。本研究共纳入了120名因心肌梗死入住西里西亚心脏病中心(SCCS)的患者,身体成分分析评估了包括脂肪组织百分比(FatP)[ % ]、总脂肪组织(FatM)[ kg ]、去脂体重(FFM)[ kg ]、肌肉量(PMM)[ kg ]、全身水含量(TBW)[ kg ]和内脏脂肪组织(VFAT)在内的各种参数。整个组的平均BMI为27.76±4.08,女性的值明显低于男性(26.66±3.33对28.16±4.27)。WHR、WHtR、BAI和VAI的平均值分别为0.97±0.08、0.59±0.07、28.37±5.03和3.08±3.50。根据内脏脂肪指数(VAI),47.5%的患者没有脂肪组织功能障碍,女性的比例(71.88%)高于男性(38.64%)。令人担忧的是,32.50%的患者有急性脂肪组织功能障碍,男性的患病率(38.64%)明显高于女性(15.63%)。结论:研究结果表明,BMI、WC和WHR有其局限性,而WHtR、VAI和BAI能更全面地反映心脏代谢风险,特别是在脂肪组织分布及其代谢后果方面。将WHtR、VAI和BAI纳入常规临床实践可能会加强心脏代谢风险的管理,尤其是在心肌梗死后患者中。

相似文献

4
Sensitivity of various adiposity indices in identifying cardiometabolic diseases in Arab adults.
Cardiovasc Diabetol. 2015 Aug 7;14:101. doi: 10.1186/s12933-015-0265-5.
5
SUITABILITY OF VISCERAL ADIPOSITY INDEX AS A MARKER FOR CARDIOMETABOLIC RISKS IN JORDANIAN ADULTS.
Nutr Hosp. 2015 Dec 1;32(6):2701-9. doi: 10.3305/nh.2015.32.6.9543.
7
Visceral adiposity index (VAI) is predictive of an altered adipokine profile in patients with type 2 diabetes.
PLoS One. 2014 Mar 20;9(3):e91969. doi: 10.1371/journal.pone.0091969. eCollection 2014.

本文引用的文献

2
Visceral Adiposity Index as a Measure of Cardiovascular Disease in Persons With Human Immunodeficiency Virus.
Open Forum Infect Dis. 2023 Jul 24;10(8):ofad398. doi: 10.1093/ofid/ofad398. eCollection 2023 Aug.
3
Body composition and risk factors for cardiovascular disease in global multi-ethnic populations.
Int J Obes (Lond). 2023 Sep;47(9):855-864. doi: 10.1038/s41366-023-01339-9. Epub 2023 Jul 17.
6
Risk of early recurrence and mortality in high-risk myocardial infarction patients: A population-based linked data study.
Int J Cardiol Cardiovasc Risk Prev. 2023 Apr 6;17:200185. doi: 10.1016/j.ijcrp.2023.200185. eCollection 2023 Jun.
7
A Systematic Review of Lipid Management in Secondary Prevention and Comparison of International Lipid Management Pathways.
Cureus. 2023 Feb 25;15(2):e35463. doi: 10.7759/cureus.35463. eCollection 2023 Feb.
10
Association between visceral adiposity index and heart failure: A cross-sectional study.
Clin Cardiol. 2023 Mar;46(3):310-319. doi: 10.1002/clc.23976. Epub 2023 Jan 18.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验