Briggs J E, Patel H, Butterfield K, Honeybourne D
Department of Thoracic Medicine, Dudley Road Hospital, Birmingham, U.K.
Respir Med. 1990 Jan;84(1):43-6. doi: 10.1016/s0954-6111(08)80093-5.
Subjects with chronic obstructive airways disease may have difficulty with the roadside alcolmeter. Twenty-six subjects with a FEV1/FVC less than 60% were asked to use an alcolmeter simulator. Only ten were able to produce the necessary flow rate of 28 l min-1 for a minimum of 2.7 s, two could produce the same total volume (1.25 l) at 10 l min-1 for 7.5 s, five could only expel 10 l min-1 for 4.5 s, and nine were unable to trigger the alcolmeter at even these very low flow rates. Subjects with an FEV1 of less than 1.51 or FEV1% predicted less than 50% were very unlikely to be able to activate the alcolmeter. Ten healthy subjects were investigated to assess the accuracy of the roadside alcolmeter at a flow rate of 10 l min-1 compared to 40 l min-1. No significant difference was found in breath alcohol levels between the two flow rates. It is proposed that some modification could be made to the roadside alcolmeter, without affecting its accuracy, to allow some subjects with chronic obstructive lung disease to activate the device. A postal survey of 284 subjects with a FEV1/FVC less than 60% was carried out. Of those who were drivers or exdrivers, 24.7% had had to stop or reduce their driving because of their respiratory disease. This group had a significantly lower FEV1% predicted (P = 0.035) than those whose driving was unaffected.
患有慢性阻塞性气道疾病的受试者使用路边酒精检测仪可能会有困难。26名第一秒用力呼气容积（FEV1）与用力肺活量（FVC）之比小于60%的受试者被要求使用酒精检测仪模拟器。只有10人能够以28升/分钟的必要流速持续至少2.7秒，2人能够以10升/分钟的流速持续7.5秒呼出相同的总体积（1.25升），5人只能以10升/分钟的流速呼出4.5秒，还有9人即使在这些非常低的流速下也无法触发酒精检测仪。FEV1小于1.5升或预测FEV1%小于50%的受试者极不可能激活酒精检测仪。对10名健康受试者进行了调查，以评估路边酒精检测仪在10升/分钟流速与40升/分钟流速下的准确性。两种流速下呼出气体中的酒精含量没有显著差异。建议对路边酒精检测仪进行一些修改，在不影响其准确性的情况下，使一些患有慢性阻塞性肺病的受试者能够激活该设备。对284名FEV1/FVC小于60%的受试者进行了邮寄调查。在那些目前或曾经是司机的人中，24.7%的人由于呼吸系统疾病不得不停止或减少驾驶。与驾驶未受影响的人相比，这组人的预测FEV1%显著更低（P = 0.035）。
